Publications by authors named "Puri Safitri Hanum"

Purpose: The Sinovac and AstraZeneca vaccines are the primary coronavirus disease 2019 vaccines in Indonesia. Antibody levels in vaccine-injected individuals will decline substantially over time, but data supporting the duration of such responses are limited. Therefore, this study aims to quantitatively evaluate antibody responses resulting from the completion of Sinovac and AstraZeneca administration in Indonesian adults.

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Article Synopsis
  • The study investigates the effectiveness of particulate versus non-particulate steroids in periarticular injections for pain relief after total knee replacement (TKR) surgery.
  • A network meta-analysis was performed, including 10 studies out of 108, focusing on pain reduction measured by the Visual Analog Scale (VAS) at different postoperative days (POD).
  • Results indicated that there was no significant difference in pain management between the two types of steroids, suggesting that the specific type of steroid used may have a more substantial impact on postoperative pain reduction.
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The clinical manifestations associated with COVID-19 disease is mainly due to a dysregulated host response related to the overexpression of inflammatory markers. Until recently, only remdesivir had gained FDA approval for COVID-19 hospitalized patients and there are currently no evidence-based therapeutic options or options for prevention of complications that have been established. Some medical treatments such as antivirals, antibacterials, antithrombotics, antipyretics, corticosteroids, interleukin inhibitors, monoclonal antibodies, convalescent plasma, immunostimulants, and vitamin supplements have been utilized.

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