Publications by authors named "Pupillo G"

Many-particle entanglement is a key resource for achieving the fundamental precision limits of a quantum sensor. Optical atomic clocks, the current state of the art in frequency precision, are a rapidly emerging area of focus for entanglement-enhanced metrology. Augmenting tweezer-based clocks featuring microscopic control and detection with the high-fidelity entangling gates developed for atom-array information processing offers a promising route towards making use of highly entangled quantum states for improved optical clocks.

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are considered valuable sentinel Gram-positive bacteria for monitoring vancomycin antibiotic resistance due to their widespread presence and characteristics. The use of antimicrobials in farming animals has a role in the increasing of Antimicrobial Resistance (AMR) and the anthropogenic transformation of the landscape has forced wildlife into greater contact with humans and their livestock. The transmission of resistant bacteria by their meat products is a significant contributor to AMR development.

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Background: The integration of positron emission tomography (PET) and magnetic resonance imaging (MRI) holds promise for advancing diagnostic imaging capabilities. The METRICS project aims to develop cyclotron-driven production of Mn for PET/MRI imaging.

Results: Using the Cr(p,n)Mn reaction, we designed chromium metal targets via Spark Plasma Sintering and developed a separation procedure for isolating Mn.

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Article Synopsis
  • Research in Italy has found group B Streptococcus causing illness in both farmed pigs and wild porcupines.
  • In pigs, the infection is likely due to transmission from nonpasteurized bovine milk whey.
  • The study reveals that porcupines have a different source of infection, highlighting the diverse host range for this bacterium.
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The cross-sections of the Ti(p,x)Sc, Sc, Sc, Sc, Sc, and V nuclear reactions were measured from 18 to 70 MeV, with particular attention to Sc production. Enriched Ti powder was deposited on an aluminum backing and the obtained targets were characterized via elastic backscattering spectroscopy at the INFN-LNL. Targets were exposed to low-intensity proton irradiation using the stacked-foils technique at the ARRONAX facility.

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  • Second-generation anticoagulant rodenticides (ARs) are commonly used for pest control and have been shown to affect carnivores, particularly small and mesocarnivores, but the impact on large carnivores like wolves has not been thoroughly studied.
  • A study in central and northern Italy found that 61.8% of tested grey wolves showed exposure to ARs, with increasing levels of contamination linked to more urbanized areas and rising trends over time, especially post-2020.
  • The results highlight a significant conservation threat for large carnivores, indicating the need for urgent monitoring of AR contamination to protect species like wolves from unintentional poisoning in human-altered environments.
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Pleuromutilins (tiamulin and valnemulin) are often used to treat swine dysentery due to recurrent resistance to macrolides and lincosamides. Recently, reduced susceptibility of B. hyodysenteriae to pleuromutilin has been reported.

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In recent years, the growth of wild ungulates has increased the focus on their health monitoring. In particular, the health status of wild boars is relevant for the economic impact on the pig industry. The Emilia-Romagna region activated a wildlife monitoring plan to better evaluate the health status of the wild boar population.

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Article Synopsis
  • * Research into new atomic species, like alkaline earth atoms, is being explored to enhance coherence and scalability, crucial for quantum error correction techniques.
  • * The study introduces a neutral atom qubit based on a long-lived state in Yb, achieving high accuracy in quantum gate operations and effectively managing errors through mid-circuit detection, indicating Yb's potential for fault-tolerant quantum computing.
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We analyze the propagation of excitons in a d-dimensional lattice with power-law hopping ∝1/r^{α} in the presence of dephasing, described by a generalized Haken-Strobl-Reineker model. We show that in the strong dephasing (quantum Zeno) regime the dynamics is described by a classical master equation for an exclusion process with long jumps. In this limit, we analytically compute the spatial distribution, whose shape changes at a critical value of the decay exponent α_{cr}=(d+2)/2.

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The recent expansion of the habitat of several wildlife species, comprising anthropized areas, is a relevant risk factor for many zoonotic diseases and should be considered in national and regional sanitary monitoring systems. We evaluated adult intestinal spp. parasites isolated from wild carnivores and cystic larval forms isolated from wild mammals analysed at the (IZSLER) as part of the regional wildlife sanitary surveillance plan.

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All-to-all interacting, disordered quantum many-body models have a wide range of applications across disciplines, from spin glasses in condensed-matter physics over holographic duality in high-energy physics to annealing algorithms in quantum computing. Typically, these models are abstractions that do not find unambiguous physical realizations in nature. Here we realize an all-to-all interacting, disordered spin system by subjecting an atomic cloud in a cavity to a controllable light shift.

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The realization of isotopically enriched Ti targets for nuclear cross-section measurements requires particular attention, from the starting material preparation up to the deposition technique. In this work, a cryomilling process was developed and optimized, aimed at reducing the size of Ti metal sponge as provided by the supplier (size up to 3 mm), to the optimal size of 10 µm, to fit the High Energy Vibrational Powder Plating technique used for target manufacturing. The optimization of the cryomilling protocol and the HIVIPP deposition using Ti material was thus performed.

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In the last decade, an upsurge of human leishmaniasis has been reported in the Emilia-Romagna region, Northeast Italy. Epidemiologic data have raised doubts about the role of dogs as the main reservoirs for . In the present study, a total of 1,077 wild animals were screened for DNA in earlobe and spleen samples from 2019 to 2022.

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The nematode is a cosmopolitan parasite capable of infecting both birds and mammals including humans. has a limited zoonotic importance in comparison to that of the other species. However, it has been recognized as the etiological agent of two outbreaks of trichinellosis due to the consumption of wild boar meat.

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(group B Streptococcus, GBS) is a causative agent of mastitis in dairy cattle, mainly causing a subclinical disease associated with a high somatic cell count (SCC), and a consequent decrease in production yield and quality of milk. GBS has been almost eradicated in many Northern European countries, but there are warnings of its re-emergence as a zoonotic threat. In Italy, only two regions carry out a GBS control program: Lombardy and Emilia-Romagna.

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A systematic surveillance against influenza A viruses (IAVs) in the population is essential, considering their role as IAV mixing vessels. However, the viral circulation in wild species is poorly investigated in comparison to the knowledge of IAV infection dynamics in domestic pigs. This study investigated the circulation and the genetic diversity of wild boars' IAVs detected in the Emilia-Romagna region (2017-2022).

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In the absence of frustration, interacting bosons in their ground state in one or two dimensions exist either in the superfluid or insulating phases. Superfluidity corresponds to frictionless flow of the matter field, and in optical conductivity is revealed through a distinct δ-functional peak at zero frequency with the amplitude known as the Drude weight. This characteristic low-frequency feature is instead absent in insulating phases, defined by zero static optical conductivity.

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Is the Cu production worldwide feasible for expanding preclinical and clinical studies? How can we face the ingrowing demands of this emerging and promising theranostic radionuclide for personalized therapies? This review looks at the different production routes, including the accelerator- and reactor-based ones, providing a comprehensive overview of the actual Cu supply, with brief insight into its use in non-clinical and clinical studies. In addition to the most often explored nuclear reactions, this work focuses on the Cu separation and purification techniques, as well as the target material recovery procedures that are mandatory for the economic sustainability of the production cycle. The quality aspects, such as radiochemical, chemical, and radionuclidic purity, with particular attention to the coproduction of the counterpart Cu, are also taken into account, with detailed comparisons among the different production routes.

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Purpose: Cu and Cu radioisotopes have nuclear characteristics suitable for nuclear medicine applications. The production of Cu is already well established. However, the production of Cu in quantities suitable to conduct clinical trials is more challenging as it leads to the coproduction of other Cu isotopes, in particular Cu.

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We study a simple model for photoinduced electron transfer reactions for the case of many donor-acceptor pairs that are collectively and homogeneously coupled to a photon mode of a cavity. We describe both coherent and dissipative collective effects resulting from this coupling within the framework of a quantum optics Lindblad master equation. We introduce a method to derive an effective rate equation for electron transfer by adiabatically eliminating donor and acceptor states and the cavity mode.

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Sc is one of the most promising theranostic radionuclides, thanks to its low energy γ-ray emission (159 keV), suitable for single photon emission computed tomography imaging and its intense β emission, useful for tumour treatment. Despite promising preclinical results, the translation of Sc-therapeutic agents to the clinic is hampered by its limited availability. Among different Sc-production routes currently being investigated, the V(p,x)Sc reaction has proved to be of particular interest, thanks to the low-cost and easy availability on the market of V material and the diffusion of medium energy proton cyclotrons.

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We present a sufficient criterion for the emergence of cluster phases in an ensemble of interacting classical particles with repulsive two-body interactions. Through a zero-temperature analysis in the low density region we determine the relevant characteristics of the interaction potential that make the energy of a two-particle cluster-crystal become smaller than that of a simple triangular lattice in two dimensions. The method leads to a mathematical condition for the emergence of cluster crystals in terms of the sum of Fourier components of a regularized interaction potential, which can be in principle applied to any arbitrary shape of interactions.

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We propose a mechanism to realize high-yield molecular formation from ultracold atoms. Atom pairs are continuously excited by a laser, and a collective decay into the molecular ground state is induced by a coupling to a lossy cavity mode. Using a combination of analytical and numerical techniques, we demonstrate that the molecular yield can be improved by simply increasing the number of atoms, and can overcome efficiencies of state-of-the-art association schemes.

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Despite interesting properties, the use of Cu, Re and Sc theranostic radionuclides in preclinical studies and clinical trials is curtailed by their limited availability due to a lack of widely established production methods. An IAEA Coordinated Research Project (CRP) was initiated to identify important technical issues related to the production and quality control of these emerging radionuclides and related radiopharmaceuticals, based on the request from IAEA Member States. The international team worked on targetry, separation, quality control and radiopharmaceutical aspects of the radionuclides obtained from research reactors and cyclotrons leading to preparation of a standard recommendations for all Member States.

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