The influence of air pollution on skin microbiome: a link to skin barrier dysfunction.

An equilibrium of skin microbiome is crucial for maintaining skin barrier function. However, external factors such as air pollution have the potential to disrupt this equilibrium. Hence, further investigation into the influence of air pollution on the skin microbiome emerges as a critical imperative.

The efficacy of light-guiding microneedle patch for stimulating hair growth in androgenetic alopecia.

Androgenetic alopecia (AGA) is the most common form of hair loss characterized by miniaturization of hair follicles. Low-level light therapy (LLLT) and microneedling have shown potential in promoting hair regrowth. This study aims to evaluate the efficacy of an innovative light-emitting diode (LED) helmet cooperated with a novel light-guiding microneedle patch (LMNP) for stimulating hair growth in AGA.

The efficacy of LED microneedle patch on hair growth in mice.

Light penetration depth in the scalp is a key limitation of low-level light therapy for the treatment of androgenetic alopecia (AGA). A novel light emitting diode (LED) microneedle patch was designed to achieve greater efficacy by enhancing the percutaneous light delivery. The study aimed to investigate the efficacy and safety of this device on hair growth in mice.

Efficacy of a novel microneedle patch for rejuvenation of the nasolabial fold.

Background: Skin rejuvenation plays a significant role in the esthetic medicine market. Microneedle patches have been developed for a wide range of applications based on the principles of transdermal drug delivery; however, clinical trials of microneedle patches for skin rejuvenation remain limited.

Aims: This study was conducted to examine the efficacy of microneedle patches for improving nasolabial folds.

The Efficacy and Safety of Epidermal Growth Factor Combined with Fractional Carbon Dioxide Laser for Acne Scar Treatment: A Split-Face Trial.

Background: Epidermal growth factor (EGF) stimulates collagen production and supports the wound healing process. However, there are no studies on fractional carbon dioxide (CO) laser combined with EGF for acne scar treatment.

Objective: We sought to evaluate the efficacy and safety of fractional CO laser combined with topical EGF versus fractional CO laser alone in the treatment of acne scars.

A novel technique in reducing sebum production and improving atrophic acne scars.

Objective: Fractional microneedling radiofrequency (FMR) has gained popularity for the treatment of acne scars, owing to favorable outcomes and short downtimes. This study aimed to investigate FMR use in reducing facial sebum production and treating acne scars.

Materials And Methods: This single-center, prospective, evaluator-blinded trial compared sebum production after three sessions of FMR (Fractora® 24-pin coated tip) performed one-month apart.

Intradermal Tranexamic Acid Injection for the Treatment of Melasma: A Pilot Study with 48-week Follow-up.

Despite being an effective treatment for melasma, there have been limited reports on the long-term efficacy of intradermal tranexamic acid (TA) injection. This study sought to evaluate the 48-week efficacy of a 4mg/mL intradermal TA injection for the treatment of melasma. Five female patients with melasma participated in the 48-week follow-up after receiving 4-mg/mL intradermal TA injections on the face every two weeks for seven sessions and a sunscreen prescription.

Comparison of Fractional Picosecond 1064-nm Laser and Fractional Carbon Dioxide Laser for Treating Atrophic Acne Scars: A Randomized Split-Face Trial.

Background: To date, no studies have compared the fractional picosecond 1064-nm laser (FxPico) and fractional carbon dioxide laser (FxCO2) for the treatment of acne scars.

Objective: To compare the efficacy and safety between FxPico and FxCO2 for treating facial atrophic acne scars.

Materials And Methods: Twenty-five Asian patients with mild to moderate atrophic acne scars underwent single sessions of randomized split-face treatment with FxPico and FxCO2.

Ultraviolet filters in sunscreen products labeled for use in children and for sensitive skin.

Background: The active ingredients in sunscreen products are ultraviolet (UV) filters, many of which are known potential allergens. The use of sunscreen in younger children and individuals with sensitive skin requires special attention, since absorption and allergen sensitization are of concern.

Objective: This study aims to evaluate the ultraviolet filters in sunscreen products labeled specifically for "kids" or as "sensitive/hypoallergenic" and compare these to general sunscreen products.

Platelet-rich plasma treatment for melasma: A pilot study.

Background: Melasma treatments have varying success and are associated with some complications.

Aims: To assess the effectiveness of platelet-rich plasma (PRP) treatment for melasma.

Methods: Ten female patients with bilateral mixed-type melasma were enrolled in our randomized, split-face, single-blinded prospective trial.

Split face comparison between common concentration vs double dilution of intradermal abobotulinum toxin type A (Dysport) injection for facial lifting in Asians.

Background: The most efficacious concentration of botulinum toxin for facial lifting is not well established.

Objective: This study compared the efficacy of common concentration vs double dilution of intradermal abobotulinum toxin type A (Dysport) injection for facial lifting in Asians.

Methods: In all, 10 women aged 32-61 years with mild to moderate facial laxity participated in this study.

Intradermal tranexamic acid injections to prevent post-inflammatory hyperpigmentation after solar lentigo removal with a Q-switched 532-nm Nd:YAG laser.

: Post-inflammatory hyperpigmentation (PIH) after solar lentigo removal using a Q-switched (QS) 532-nm Nd:YAG laser is a cause for concern. This study aimed to evaluate the efficacy and safety of intradermal injections of tranexamic acid (TA) at reducing the risk of PIH after QS 532-nm Nd:YAG laser treatment of solar lentigines. : Twenty-five patients with 50 solar lentigines on forearms underwent QS 532-nm Nd:YAG laser treatment.

A Novel Technique of Supra Superficial Musculoaponeurotic System Hyaluronic Acid Injection for Lower Face Lifting.

Background: Various methods attempting to correct sagging of the lower face focus mainly on manipulation of the superficial musculoaponeurotic System. Each technique has its own limitation. The authors propose a relatively simple, conservative method utilizing hyaluronic acid injection just above the superficial musculoaponeurotic System.

Treatment of melasma in men with low-fluence Q-switched neodymium-doped yttrium-aluminum-garnet laser versus combined laser and glycolic acid peeling.

Background: Low-fluence Q-switched neodymium-doped yttrium-aluminum-garnet 1,064-nm laser (LFQS) and glycolic acid (GA) peeling have been reported as a treatment option for melasma. However, there are limited data on their efficacy in men.

Objective: To compare the efficacy and safety of LFQS monotherapy with combined LFQS and 30% GA peeling in male patients with melasma.

The 'pantie' tumour.

We present a case of radiation-associated angiosarcoma. A 67-year-old Thai woman was diagnosed with endometrium carcinoma stage IC and was treated with surgery and radiations. Ten years later, she presented with a gradually enlarging mass on the pubic area, in the shape of a pair of panties.