Publications by authors named "Punnanee Wutthigate"
Article Synopsis
- * Researchers analyzed data from 233 cases of fetal CHD and 466 control pregnancies, finding a significantly higher risk of spontaneous preterm labor, early delivery, and pre-eclampsia in CHD cases.
- * Prenatal diagnosis of CHD was linked to a lower risk of preterm delivery, emphasizing the need for early detection and specialized care to enhance pregnancy and neonatal outcomes.
Article Synopsis
- Premature infants with bronchopulmonary dysplasia (BPD) are at risk for pulmonary hypertension (PH), and this study explores the connection between patent ductus arteriosus (PDA) management strategies and the prevalence of BPD-PH.
- The research involved examining newborns under 29 weeks gestational age with BPD across two centers—one with a conservative PDA approach and the other with a more aggressive treatment method.
- Findings indicated similar rates of PH between the two centers despite different PDA treatment rates, suggesting that a conservative approach does not increase the likelihood of PH diagnosis in these infants.
Article Synopsis
- The study aimed to identify specific fetal echocardiography markers that can accurately predict coarctation of the aorta (CoA) in newborns, as current diagnostic methods have a high rate of false positives.
- Researchers conducted a retrospective case-control study comparing various echocardiographic measurements of infants who required treatment for CoA after birth with those who did not, stratifying results based on gestational age (GA).
- Results showed that specific ratios of right to left ventricular dimensions and deformation parameters are the most effective predictors of true CoA, particularly the RV/LV end-diastolic area ratio, which identified all cases of CoA with a high sensitivity.
Article Synopsis
- - The study investigated how early cardiac function impacts outcomes like death and severe bronchopulmonary dysplasia (BPD) in extremely premature infants born before 29 weeks, through a retrospective analysis of 176 infants from 2015 to 2019.
- - Findings revealed that infants who experienced death/severe BPD had lower birth weights and showed reduced heart function on echocardiograms taken within 21 days, with specific measurements indicating worse cardiac performance and potential pulmonary issues.
- - The research concluded that diminished cardiac function early in life correlates with increased risks of severe BPD and related pulmonary hypertension, suggesting the importance of monitoring heart health in neonates and its potential role in predicting outcomes.
Article Synopsis
- The study investigated how the degree of prematurity (specifically the gestational age at birth) affects cardiac size and function in extremely preterm infants at near-term age.
- Researchers analyzed data from infants born at less than 29 weeks of gestational age, comparing those born before and after 26 weeks.
- Results showed that infants born before 26 weeks had significantly smaller left heart dimensions compared to their slightly more mature counterparts, highlighting potential long-term cardiac concerns.
Article Synopsis
- The study aimed to compare vascular flow trends in the anterior cerebral artery (ACA) of neonates with congenital heart defects (CHD), focusing on those with and without diastolic systemic steal during their first week of life.
- Researchers used Doppler ultrasound and echocardiography to analyze 38 neonates daily from day 1 to 7, categorizing them based on the presence of retrograde flow in the aorta.
- Results showed that while peak systolic and mean velocities increased over time regardless of retrograde status, those with retrograde flow experienced a significant decrease in ACA-end-diastolic velocity and increases in resistive and pulsatility indexes, indicating cerebrovascular steal in the first week of life.
Article Synopsis
- The study aimed to assess the factors linked to significant pulmonary hypertension (PH) in infants born prematurely and how it affects their heart function at 36 weeks postmenstrual age (PMA).
- Out of 387 infants, 222 were studied, with 24 (11%) showing significant PH, which was linked to lower heart function metrics, including reduced tricuspid annular plane systolic excursion and peak longitudinal strain in both the right and left ventricles.
- The results indicate that premature infants with significant PH experience changes in heart function affecting both sides of the heart, highlighting a deeper cardiac issue related to their PH condition.
Background: Plugged milk duct during lactation is a common problem in breastfeeding. Traditional breast massage (TBM) has been performed in Thailand with reasonable outcomes, but several follow-up sessions are often required. A new massage technique, the integrated breast massage (IBM), was subsequently developed.
View Article and Find Full Text PDFEarly Echocardiography Predicts Intervention Need in Antenatal Suspicion of Coarctation of the Aorta.
CJC Pediatr Congenit Heart Dis
August 2022
Article Synopsis
- Coarctation of the aorta (CoA) is tough to spot in newborns, but researchers studied infants suspected of having CoA to understand resource use and intervention needs.
- In a study of 51 infants, only 11 needed cardiac surgery, while 40 were considered normal, with echocardiograms done within the first day of life.
- Key findings suggest that a specific left-to-right ventricular size ratio could effectively predict which infants actually have CoA, helping identify those who need intervention early on.
Article Synopsis
- The study aimed to assess the spontaneous closure of patent ductus arteriosus (PDA) in extremely preterm infants, particularly those born before 26 weeks gestational age, and its impact on their respiratory health.
- A retrospective analysis was conducted on 214 extremely preterm infants admitted shortly after birth, with significant findings showing that 91% experienced spontaneous PDA closure, including 90% of those <26 weeks.
- The results indicated not only high closure rates by term corrected age but also a notable reduction in occurrences of moderate-to-severe bronchopulmonary dysplasia over the study period.
Accuracy of transcutaneous bilirubin measured by the BiliCare device in late preterm and term neonates.
J Matern Fetal Neonatal Med
November 2016
Article Synopsis
- This study examines the effectiveness of a new device, the BiliCare™ bilirubinometer, for screening jaundice in infants.
- The study involved 114 paired bilirubin measurements in 93 healthy infants, showing the TCB had a consistent performance compared to serum bilirubin levels.
- Results indicate that while the device is useful for detecting jaundice, careful selection of cut-off levels is crucial due to some inaccuracies.