Patient-specific mechanical analysis of PCL periodontal membrane: Modeling and simulation.

This research fills a knowledge gap in bone tissue engineering by examining the mechanical characteristics of scaffolds at bone-tissue interfaces utilizing a cutting-edge technique involving the creation of 3D scaffolds from Polycaprolactone (PCL). The work employs Finite element analysis to measure the scaffolds' maximum principal and Von Mises stresses and strains. CT scans of the Maxilla and Mandible were used to apply load conditions to 3D models of the upper central incisor.

Expression of p-16, Ki-67 and p-53 markers in dysplastic and malignant lesions of the oral cavity and oropharynx.

Background: Understanding the markers for predicting degree of dysplasia and progression to malignancy can help early identification and prompt treatment of patients with oral cancers. In this study, we aim to identify and characterize different tumor suppressor genes such as p-53 and p-16 and proliferation marker Ki-67 in defining stages of dysplasia of oral mucosa and grading of tumor.

Settings And Design: Oral biopsy tissues (for neoplastic lesions) received for histopathological evaluation were included in the study.

Heterogeneous modeling based prosthesis design with porosity and material variation.

The work proposes the development of heterogeneous bio-implants with the aim to minimize stress shielding effect and enhance bone ingrowth. Stress shielding in the implant can be minimized by reducing the overall stiffness of the implant, which is achieved here by varying the material based on stress distribution across the prosthesis. To increase overall stability of the implant by simultaneous enhancing osseointegration and reducing stress shielding, the work proposes the design of heterogeneous prosthesis with graded porosity and material having radial, axial and mixed (simultaneous radial and axial) variations.

Skeletal angiomatosis - rare cause of bone destruction: a case report with review of literature.

Classification of skeletal angiomatosis into aggressive and nonaggressive types is on the basis of their clinical behavior and pattern of skeletal involvement (regional and disseminated). Gorham's disease (massive osteolysis) is an aggressive form of skeletal angiomatosis that shows regional involvement, frequently involving the shoulder and hip areas. Cystic angiomatosis is a nonaggressive form of skeletal angiomatosis with multifocal involvement, predominantly affecting the trunk bones.

Congenital epulis of the newborn: a case report with review of literature.

Congenital epulis, also known as congenital gingival granular cell tumor, is a rare benign intraoral tumor found only in the new born. It can be solitary or multiple and may occur in the mandible, maxilla or tongue and may or may not be associated with other congenital anomalies. The size of the mass varies and if very large may interfere with respiration and feeding at birth, thus necessitating the immediate surgical resection at birth to maintain patency of the airways.