Publications by authors named "Pulin Luo"
Article Synopsis
- - The vaginal microbiome significantly impacts reproductive health, especially in relation to infertility and in vitro fertilization (IVF) success, as evidenced by a study involving 1411 individuals.
- - Findings indicate that a moderate abundance of specific microbes is linked to higher pregnancy rates, while both low and high abundances are associated with poorer outcomes; specifically, a moderate presence (~80%) yielded better results compared to higher abundances (>90%).
- - Analysis reveals that nonpregnant women have more antibiotic-resistance genes, suggesting potential differences in vaginal microbiomes linked to infertility, which could lead to improved IVF strategies.
Purpose: To examine the interaction between serum progesterone concentration on the trigger day and choice of freeze-all and fresh transfer strategies on live birth in an unselected population as well as in patients over 35 years old.
Methods: We performed a retrospective cohort study of 26,661 patients commencing their first IVF cycle in a large fertility centre between 2015 and 2019, including 4687 patients over 35 years old. We performed a multivariable fractional polynomial interaction analysis within a logistic regression model to investigate the interaction between serum progesterone concentration and the choice of freeze-all or fresh transfer strategy following the first transfer.