Publications by authors named "Pulikkottil Raphael Varghese"
Article Synopsis
- This study aimed to investigate the role of IRF6 gene polymorphisms in individuals with Non-syndromic Orofacial Cleft (NSOFC) in Kerala.
- The research involved analyzing DNA from 100 case-parent triads and specifically focused on the polymorphisms rs2235371 and rs7552506 using PCR and Sanger sequencing.
- Results indicated a significant association between rs2235371 and NSOFC, particularly linked to paternal ancestry, while rs7552506 exhibited maternal linkage, suggesting IRF6 could be a risk factor for NSOFC in this population.
Background: Vaccine effectiveness for first-generation coronavirus disease (COVID-19) vaccines among People Living with HIV (PLHIV) in India remains unexplored. This study entails the estimation of the real-world effectiveness of COVID-19 vaccines (AZD1222/Covishield, BBV152/Covaxin) among PLHIV and the identification of variants of SARS-CoV-2 among those infected with COVID-19.
Methods: An ambi-directional cohort study was conducted among 925 PLHIV above 18 years of age in two districts of central Kerala, India, from February 2022 to March 2023.
Owing to COVID 19 pandemic, all educational institutions including medical colleges were closed by the second week of March 2020 in Kerala, India. This college started online classes using various e-platforms by the third week of March. In this study, we report the barriers and perceptions of undergraduate students by an online questionnaire after 2.
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