Publications by authors named "Puliatti S"
Objectives: To examine critical care therapy rates after cytoreductive nephrectomy in metastatic kidney cancer patients.
Design, Setting, And Patients: Relying on the National Inpatient Sample (2000-2019), we addressed critical care therapy use (total parenteral nutrition, invasive mechanical ventilation, renal replacement therapy, percutaneous endoscopic gastrostomy tube insertion, and tracheostomy) and in-hospital mortality in surgically treated metastatic kidney cancer patients. Estimated annual percentage changes and multivariable logistic regression models were fitted.
Survival differences in rare histological prostate cancer (PCa) subtypes relative to age-matched population-based controls are unknown. Within Surveillance, Epidemiology, and End Results database (2004-2020), newly diagnosed (2004-2015) PCa patients were identified. Relying on the Social Security Administration Life Tables (2004-2020) with 5 years of follow-up, age-matched population-based controls (Monte Carlo simulation) were simulated for each patient.
View Article and Find Full Text PDFObjective: This study aimed to compare adverse in-hospital outcomes in ileal conduit versus neobladder urinary diversion type after radical cystectomy (RC) in contemporary versus historical patients.
Methods: Patients were identified within the National Inpatient Sample (NIS 2000-2019). Propensity score matching (PSM; 1:2 ratio) and multivariable logistic regression models (LRMs) were used.
Background: Perioperative complication rates and in-hospital mortality after radical nephroureterectomy (RNU) in patients with a history of heart valve replacement are unknown.
Methods: Within the National Inpatient Sample (2000-2019), we identified non-metastatic upper urinary tract carcinoma patients treated with RNU according to the presence or absence of a history of heart valve replacement. Propensity score matching (1:10 ratio) and multivariable logistic regression as well as Poisson regression models were used.
Background: The aim of this study was to validate lymphovascular invasion (LVI) as a predictor of lymph-node invasion (LNI) in squamous cell carcinoma of the penis (SCCP).
Methods: Within the Surveillance, Epidemiology, and End Results database (2010-2020), we identified SCCP patients who underwent lymphadenectomy with known LVI status. Univariable logistic regression models (LRMs) addressed LNI.
Objective: To conduct a population-based study examining cancer-specific mortality (CSM) and other-cause mortality (OCM) differences in patients with radiation-induced secondary bladder cancer (RT-BCa) vs those with primary bladder cancer (pBCa) undergoing radical cystectomy (RC).
Methods: Within the Surveillance, Epidemiology, and End Results database (2004-2020), we identified patients with TNM bladder cancer treated with RC, who had previously been treated with external beam radiation therapy (EBRT) or brachytherapy for prostate cancer, as well as patients with TNM pBCa treated with RC. Cumulative incidence plots and multivariable competing risks regression (CRR) models were used to assess CSM after additional adjustment for OCM.
Background: Over the past decade, the range of surgical options to benign prostatic obstruction (BPO) has expanded significantly with the advent of minimally invasive surgical therapies (MISTs). Nevertheless, the available evidence in the field is heterogeneous. Efficacy and safety thresholds are yet to be determined.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the use of critical care therapies (CCT) like invasive mechanical ventilation and total parenteral nutrition in patients following radical nephroureterectomy for upper urinary tract carcinoma, revealing an unclear relationship with in-hospital mortality.
- An analysis of 8,995 non-metastatic UUTC patients from 2008-2019 found that 4.2% received CCT, with a notable correlation between the rates of CCT and in-hospital mortality over time.
- Findings suggest that CCT is more common among older and sicker patients, while a decline in CCT and mortality rates indicates improvements in care quality, with an ideal scenario showing that in-hospital deaths should follow CCT exposure.
Article Synopsis
- This study looked at two types of cancer treatment: Trimodal Therapy (TMT) and External Beam Radiation Therapy (EBRT) for bladder cancer patients.
- It found that TMT helped more patients live longer compared to EBRT, especially in those with earlier stages of cancer.
- However, TMT didn't show a survival advantage in patients with more advanced cancer stages.
Article Synopsis
- * In healthcare, it can help with things like training surgeons using virtual worlds, planning surgeries with 3D models, and guiding surgeons during operations.
- * There are exciting possibilities ahead, like better patient care through monitoring and education, but we need to solve issues with data security before diving in fully.
Article Synopsis
- This study analyzed the clinicopathologic characteristics and treatment patterns of adult prostate sarcoma patients using data from the Surveillance, Epidemiology, and End Results database between 2004 and 2020.
- Among 125 patients, the most common subtype was leiomyosarcoma (36%), with rhabdomyosarcoma (14%) being more likely to present at a metastatic stage compared to other types.
- The overall median survival was 27 months, with treatment approaches differing significantly based on the subtype; metastatic disease was linked to higher mortality rates, while stromal sarcoma had a lower overall mortality risk.
Article Synopsis
- The surgical training landscape is shifting from traditional methods to more scientific ones, particularly in robot-assisted surgeries like radical prostatectomy (RARP), to enhance safety and efficiency.
- The review highlights a lack of standardized curricula for RARP training, despite the increasing adoption of robotic surgery and its associated risks, underscoring the need for structured training programs.
- Various training stages, including e-learning, virtual simulators, and hands-on labs, are essential to equip surgeons with the unique skills needed for successful robotic surgeries.
Race/Ethnicity Affects Access and Survival Differences After Neoadjuvant or Adjuvant Chemotherapy at Radical Cystectomy in Urothelial Carcinoma Patients.
J Racial Ethn Health Disparities
August 2024
Introduction: It is unknown whether race/ethnicity affects access and/or survival after neoadjuvant (NAC) or adjuvant chemotherapy (ADJ) at radical cystectomy (RC). We addressed these knowledge gaps.
Material And Methods: Within the Surveillance, Epidemiology, and End Results database (2007-2020), we identified NAC candidates (T2-T4N0M0) and ADJ candidates (T3-T4 and/or N1-3).
Introduction: Donor nephrectomy (DN) is a unique surgical procedure in urological practice, as it involves exposing a healthy individual to the potential risks of surgery. This type of surgery exhibits heterogeneity in terms of approach (open, laparoscopic, or robotic), each with its unique set of advantages and disadvantages. Consequently, there is currently a lack of universally agreed upon clear guidelines.
View Article and Find Full Text PDFBackground: The purpose of this study was to test for survival differences according to adjuvant chemotherapy (AC) status in radical nephroureterectomy (RNU) patients with pT2-T4 and/or N1-2 upper tract urothelial carcinoma (UTUC).
Patients And Methods: Within the Surveillance, Epidemiology, and End Results database (SEER, 2007-2020), patients with UTUC treated with AC versus RNU alone were identified. Kaplan-Meier plots and multivariable Cox regression models addressed cancer-specific mortality (CSM).
Objective: To test the association between number as well as locations of organ-specific metastatic sites and overall survival (OS) in systhemic-therapy exposed metastatic urothelial carcinoma of urinary bladder (mUCUB) patients.
Methods: Within Surveillance, Epidemiology and End Results database (2010-2020), all systhemic therapy-exposed mUCUB patients were identified. Kaplan-Meier and multivariable Cox regression (CRM) models first addressed OS in patients according to number of metastatic organ-locations: solitary versus 2 versus 3 or more.
Background: Historical external beam radiation therapy (EBRT) for rectosigmoid cancer (RCa) predisposed patients to an increased risk of secondary bladder cancer (BCa). However, no contemporary radiotherapy studies are available. We addressed this knowledge gap.
View Article and Find Full Text PDFBackground: To assess cancer-specific mortality (CSM) and other-cause mortality (OCM) rates in patients with rare histological prostate cancer subtypes.
Methods: Using the Surveillance, Epidemiology, and End Results database (2004-2020), we applied smoothed cumulative incidence plots and competing risks regression (CRR) models.
Results: Of 827,549 patients, 1510 (0.
Article Synopsis
- The use of artificial intelligence (AI) and machine learning in urology aims to enhance diagnostic processes and improve prognosis for patients, particularly those with urolithiasis who are at risk for serious infections.
- A systematic scoping review was conducted to evaluate existing literature on AI applications for predicting infectious complications in urolithiasis, yielding nine relevant studies from an initial search of 467 articles, primarily published between 2021 and 2023.
- The reviewed studies showed promising results, with AI models like random forests and neural networks demonstrating superior performance in predicting infections compared to traditional methods, although further research and validation are necessary before widespread clinical implementation.
Article Synopsis
- Histopathological examination for cancer is time-consuming, leading to interest in ex-vivo fluorescent confocal microscopy (FCM) as a faster diagnostic tool, particularly for prostate cancer.
- A systematic review analyzed 17 studies on FCM in urology from sources like PubMed and SCOPUS, focusing on its effectiveness in diagnosing prostate cancer and assessing surgical margins.
- FCM showed a high accuracy (85.33% to 95.1%) in differentiating between cancerous and non-cancerous tissues, and its real-time capabilities may reduce the reliance on traditional frozen section analysis during surgeries.