Prevalence and prognosis of molecularly defined familial hypercholesterolemia in patients with acute coronary syndrome.

Background: Familial hypercholesterolemia (FH) can elevate serum low-density lipoprotein cholesterol (LDL-C) levels, which can promote the progression of acute coronary syndrome (ACS). However, the effect of FH on the prognosis of ACS remains unclear.

Methods: In this prospective cohort study, 223 patients with ACS having LDL-C ≥ 135.

Impact of multidisciplinary chronic disease collaboration management on self-management of hypertension patients: A cohort study.

To explore the effect of the interdisciplinary chronic disease management (CDM) model on patients with hypertension. In this intervention study, the subjects were divided into CDM and control groups. Blood pressure control was monitored in both groups.

Outcome of mitral valve repair or replacement for non-ischemic mitral regurgitation: a systematic review and meta-analysis.

Background: Mitral regurgitation (MR) is a rather common valvular heart disease. The aim of this systematic review and meta-analysis was to compare the outcomes, and complications of mitral valve (MV) replacement with surgical MV repair of non-ischemic MR (NIMR) METHODS: MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were searched until October, 2020. Studies were eligible for inclusion if they included patients with MR and reported early (30-day or in-hospital) or late all-cause mortality.

Generalized model for conic-V-shaped flexure hinges.

This paper presents a new class of flexure hinges, namely, conic-V-shaped flexure hinges (CFHs), which can be used as a generalized model for flexure hinges with profiles such as parabolic-V-shape, elliptical-V-shape, and hyperbolic-V-shape. Compliance and precision equations for the CFHs were derived as a set of nonlinear equations using Castigliano's second theorem. The parameters of the nonlinear equations inputted to the compliance and precision matrices were based on the generalized equations used for conic curves in polar coordinates.

Visfatin Level and The Risk of Hypertension and Cerebrovascular Accident: A Systematic Review and Meta-Analysis.

High blood pressure is related with increased cerebrovascular accident. High visfatin / NAMPT(nicotinamide phosphoribosyltransferase) plasma levels may promote vascular inflammation and atherosclerotic plaque destabilization and have been evaluated as a marker for identifying stages of essential hypertension. However, its role in the pathogenesis of hypertension and cerebrovascular accident (CVA) is still uncertain.