Navigating the landscape of cervical cancer in India: Epidemiology, prevention, current status, and emerging solutions.

Cervical cancer poses a significant health burden for women worldwide, particularly in India. Despite global progress, India's mortality rate, with 79 906 deaths, remains disproportionately high at approximately 11.2 per 100 000 women compared to the global average of 7.

Recurrent Giant Cell Tumour of Maxilla: A case report and review of literature.

Giant cell tumors (GCTs) are rare, locally aggressive neoplasms that commonly affect the long bones. However, GCTs can also occur in the craniofacial region, including the maxilla. This case report presents a rare case of recurrent giant cell tumor of the maxilla in a 32-year-old male patient.

A Study of the Impact and Restitutive Efforts of Cervical Cancer Screening during the COVID-19 Pandemic in a Regional Cancer Centre in Eastern India.

Aim: To evaluate the feasibility and efficacy of switching to a self-sampling based screening as compared to ongoing provider-collection based screening using HPV DNA test and assess the compliance of HPV positive women for further treatment during the COVID 19 pandemic.

Method: The study participants were women aged 30-60 years from rural and semi-urban communities around Kolkata, who underwent screening followed by HPV testing by Hybrid Capture II test. In the pre pandemic era, the women who attended the health centres where trained health workers that collected cervical samples.

Comparative Study of the Crestal vs Subcrestal Placement of Dental Implants via Radiographic and Clinical Evaluation.

Aim: The study aims at using the level/depth of implant placement (equicrestal or cretsal) as the key parameter in measuring the vertical crestal bone loss (CBL) mesially and distally, using periapical radiographs (IOPARs) taken at 1-, 3-, and 6-months interval, postprosthetic loading.

Materials And Methods: Patients ( = 40; 18-65 years), with edentulous space anteriorly or posteriorly, were randomly divided into two groups, namely, group I (equicrestal) and group II (subcrestal) with 20 patients in each group. Implants were placed at an edentulous site (delayed implants), after obtaining cone-beam computed tomography (CBCT) scans.

Evaluation of numerical rating scale and neuropathic pain symptom inventory pain scores in advanced ovarian carcinoma patients undergoing surgery and first-line chemotherapy.

Background And Aim: Advanced epithelial ovarian cancer (OC) has a high disease manifestation with difficult-to-manage symptoms that limit the patients' functionality. Abdominal pain, persistent back pain, and neuropathic pain are among the common discomforts associated with OC and its treatment. Our study aims to determine pain scores in advanced OC patients undergoing surgery and chemotherapeutic treatment with carboplatin and paclitaxel.

Assessment of quality of life among advanced ovarian cancer patients in a tertiary care hospital in India.

Purpose: The study aims to record the quality of life (Qol) and its changes while ovarian cancer (OC) patients undergo debulking surgeries and chemotherapy in a tertiary care hospital of Eastern India.

Methods: Patients with advanced epithelial OC (FIGO stages III-IV) were recruited. They underwent primary/interval debulking surgeries with classical chemotherapy (adjuvant/neoadjuvant) of intravenous tri-weekly doses of paclitaxel + carboplatin.

Experience of Human Papillomavirus Vaccination Project in a Community Set Up-An Indian Study.

Background: Initial introduction of HPV vaccination from 2006 to 2008 was largely confined to high-income countries (HIC), such as Australia, the United States, and Europe, where cervical cancer incidence is lowest. Much of the post-introduction literature has come from HICs, with a focus on coverage levels achieved, provider acceptability and early impact of vaccination on disease endpoints. However, there are a few literature evaluating the mechanics of delivery, feasibility of the health system and acceptability from low and middle income countries (LMICs).

Sinonasal IgG4-related disease: a rare and emerging entity broadening the differential diagnosis in the sinonasal universe.

Background: IgG4-related disease (IgG4-RD) is a multi-organ immune-mediated disorder characterized by fibroinflammatory mass-forming lesions, mimicking malignancy or infection. While well-documented in salivary glands, orbit and thyroid in the head and neck, sinonasal IgG4-RD is rare.

Methods: Cases of sinonasal IgG4-RD were retrieved, and clinicopathological features reviewed.

Glutathione S-transferasesP1 AA (105Ile) allele increases oral cancer risk, interacts strongly with c-Jun Kinase and weakly detoxifies areca-nut metabolites.

The Glutathione S-transferases (GSTs) protects cellular DNA against oxidative damage. The role of GSTP1 polymorphism (A313G; Ile105Val) as a susceptibility factor in oral cancer was evaluated in a hospital-based case-control study in North-East India, because the habit of chewing raw areca-nut (RAN) with/without tobacco is common in this region. Genetic polymorphism was investigated by genotyping 445 cases and 444 controls.