BMJ Support Palliat Care
September 2020
Background: A rising number of metastatic cancer patients are receiving palliative systemic therapy close to end of life. Patients started on such treatment are typically judged by oncologists to have at least 12 weeks survival, however, accurate survival prediction on individual patients is difficult. Systemic therapy started too late may not benefit patient, but rather, adversely affect patient's quality of life and may even shorten survival due to treatment-related side effects.
View Article and Find Full Text PDFBackground: The efficacy and safety of using combination chemotherapy with cetuximab as first-line treatment in patients with K-ras wild-type colorectal cancers has been well established. In general, weekly cetuximab was given with biweekly chemotherapy FOLFOX-4 or FOLFIRI, synchronizing them would be appealed to both patients and health care professionals.
Materials And Methods: This Phase II, prospective study investigated the efficacy and safety of using biweekly cetuximab 500 mg/m(2) with chemotherapy FOLFOX-4 or FOLFIRI as first-line treatment for Chinese patients with K-ras wild-type metastatic colorectal cancer.
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