Publications by authors named "Pui Yen Wong"
Article Synopsis
- The study compares the effectiveness and safety of direct oral anticoagulants (DOAC) versus warfarin for patients who underwent left atrial appendage closure in the WATCHMAN trials.
- It analyzed data from 10 cohort studies involving 2,440 patients, revealing that DOAC significantly reduced major bleeding in the immediate post-procedural period and at mid-term follow-up compared to warfarin.
- Despite these benefits, the rates of thromboembolism, all-cause mortality, device-related thrombus, and significant leaks were similar between the two treatment groups, indicating that both options are relatively safe.
Current guidelines recommend 6-12 months of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) followed by aspirin monotherapy indefinitely. We aimed to assess the efficacy and safety of clopidogrel vs aspirin in the post-PCI population after completing DAPT. We systematically searched 5 electronic databases to identify studies comparing clopidogrel with aspirin following completion of DAPT after PCI.
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