Publications by authors named "Pui Lun Yip"
Article Synopsis
- - The article discusses lupus anticoagulant (LA), which is a phenomenon causing abnormal results in blood clotting tests, specifically highlighting its association with lymphoma and IgM paraproteinaemia.
- - Two cases of low grade B-cell lymphoma were presented, both showing positive results for LA and a "lupus cofactor effect" in specific blood assays, indicating an unusual relationship between these conditions.
- - The findings suggest that diluting patient samples with normal pooled plasma is crucial for accurately evaluating LA status in cases of low grade B-cell lymphoma, as certain tests may yield false negatives without dilution.
Disseminated intravascular coagulation (DIC) is characterized by systemic activation of coagulation pathway which can lead to thrombosis and bleeding. Chronic DIC associated with aortic aneurysm or dissection commonly presents with bleeding symptoms with variable severity due to enhanced fibrinolysis. Patients with unexplained bleeding diathesis with DIC should include aortic disease as one of the differential diagnoses.
View Article and Find Full Text PDFImmunoglobulin light chain amyloidosis (AL) is a plasma cell disorder characterized by accumulation of misfolded proteins, which can induce organ damage. Venetoclax is active in multiple myeloma patients, in particular those with t(11;14) translocation. t(11;14) translocation is the most common cytogenetic abnormality in AL patients; venetoclax may thus be a useful additional treatment option for this disease.
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