"I Am Longing and Afraid to Depend on You": A Case Report on Breakdowns of Therapeutic Alliance and Interpersonal Cycles in Complex Trauma.

Background: Patients with Complex Trauma (CT) may have an impaired ability to trust others and build intimate relationships due to non-integrated representations of self and others. This sometimes leads to an oscillation between needing and fearing intimacy in their adult relationships. This dynamic can occur in the therapeutic relationship, undermining the effectiveness of therapy and affecting the mental health of both the patient and the therapist.

From the Bio-Psycho-Social Model to the Development of a Clinical-Forensic Assessment Tool for Chronic Pain in Victims of Violence: A Research Protocol.

Violence against women impacts a minimum of 35% of the global female population, encompassing sexual, physical, and psychological forms. Perpetrators of this violence include partners, family members, or strangers. Its ramifications are substantial, evident in the prevalence of chronic pain reported by between 48% and 84% of women who have experienced abuse, with an odds ratio of 2.

An Organometallic Erbium Bismuth Cluster Complex Comprising a Bi Zintl Ion.

An organometallic erbium bismuth cluster complex, [K(THF)][Cp*ErBi] (), featuring a heterometallocubane core was isolated. The cube emerges from the rare Bi Zintl ion, bridging two erbium centers for the first time. SQUID magnetometry and calculations uncovered dominant antiferromagnetic coupling enabled through the chair-like hexabismuth anion.

Time-Resolved Mechanistic Depiction of Photoinduced CO Reduction Catalysis on a Urea-Modified Iron Porphyrin.

The development of functional artificial photosynthetic devices relies on the understanding of mechanistic aspects involved in specialized photocatalysts. Modified iron porphyrins have long been explored as efficient catalysts for the light-induced reduction of carbon dioxide (CO) towards solar fuels. In spite of the advancements in homogeneous catalysis, the development of the next generation of catalysts requires a complete understanding of the fundamental photoinduced processes taking place prior to and after activation of the substrate by the catalyst.

Trends in Physical Activity and Motor Development in Young People-Decline or Improvement? A Review.

This paper aims to analyse studies and research conducted in EU and non-EU member states to identify and compare trends in physical activity and motor skills. Thus, a comparative overview of the state of the art in the two pre-pandemic decades that can facilitate an understanding of the different territorial realities and training needs to be conducted, considering the different cultural situations. A scoping review was conducted by analysing a series of studies published between 1990 and 2022, including only those studies that collected data in the pre-pandemic period.

Enthesis repair - State of play.

The fibrocartilaginous enthesis is a highly specialised tissue interface that ensures a smooth mechanical transfer between tendon or ligament and bone through a fibrocartilage area. This tissue is prone to injury and often does not heal, even after surgical intervention. Enthesis augmentation approaches are challenging due to the complexity of the tissue that is characterised by the coexistence of a range of cellular and extracellular components, architectural features and mechanical properties within only hundreds of micrometres.

SWIR digital holography and imaging through smoke and flames: unveiling the invisible.

Since its inception, digital holography has been mainly carried out using visible light but soon various other regions of the electromagnetic spectrum has been fruitfully explored. The Short Wavelength Infrared (SWIR) region, despite its interesting peculiarities and appealing applications in the imaging field, has not yet been fully investigated in Digital Holography (DH). Here we present a compact and robust SWIR DH setup and demonstrate the peculiar and remarkable advantages offered by SWIR radiation for macroscopic object investigation.

From an Isolable Bismolyl Anion to an Yttrium-Bismolyl Complex with μ-Bridging Bismuth(I) Centers and Polar Covalent Y-Bi Bonds.

Invited for the cover of this issue is the group of Selvan Demir at the Michigan State University. The cover art depicts the helicopter landing of the first crystallographically characterized bismolyl anion potassium salt in a desert oasis landscape with pyramids of elemental bismuth. Read the full text of the article at 10.

Isolation of an organometallic yttrium bismuth cluster and elucidation of its electronic structure.

A rare organometallic yttrium bismuth cluster complex with a heterometallocubane structure at the core was isolated and characterised by single-crystal X-ray diffraction analysis and UV-Vis spectroscopy. The anionic Bi core is best described as a Zintl ion. Computational exploration of its electronic structure reveals polarised Y-Bi bonds alongside delocalisation of the Bi-Bi bonds.

Physicochemical cues are not potent regulators of human dermal fibroblast trans-differentiation.

Due to their inherent plasticity, dermal fibroblasts hold great promise in regenerative medicine. Although biological signals have been well-established as potent regulators of dermal fibroblast function, it is still unclear whether physiochemical cues can induce dermal fibroblast trans-differentiation. Herein, we evaluated the combined effect of surface topography, substrate rigidity, collagen type I coating and macromolecular crowding in human dermal fibroblast cultures.

From an Isolable Bismolyl Anion to an Yttrium-Bismolyl Complex with μ-Bridging Bismuth(I) Centers and Polar Covalent Y-Bi Bonds.

The synthesis and first structural characterization of the [K(18-crown-6)] bismolyl Bi (C Me Bi) contact ion pair (1) is presented. Notably, according to Natural Resonance Theory calculations, the Bi anion of 1 features two types of leading mesomeric structures with localized anionic charge and two lone pairs of electrons at the Bi center, as well as delocalized anionic charge in the π-conjugated C Bi ring. The lone pairs at Bi enable a unique bridging coordination mode of the bismolyl ligand, as shown for the first rare earth metal bismolyl complex (Cp Y) (μ-η -Bi ) (2).

Capability accumulation patterns across economic, innovation, and knowledge-production activities.

The evolution of economic and innovation systems at the national scale is shaped by a complex dynamics related to the multi-layer network connecting countries to the activities in which they are proficient. Each layer represents a different domain, related to the production of knowledge and goods: scientific research, technology innovation, industrial production and trade. Nestedness, a footprint of a complex dynamics, emerges as a persistent feature across these multiple kinds of activities (i.

Micromotion Derived Fluid Shear Stress Mediates Peri-Electrode Gliosis through Mechanosensitive Ion Channels.

The development of bioelectronic neural implant technologies has advanced significantly over the past 5 years, particularly in brain-machine interfaces and electronic medicine. However, neuroelectrode-based therapies require invasive neurosurgery and can subject neural tissues to micromotion-induced mechanical shear, leading to chronic inflammation, the formation of a peri-electrode void and the deposition of reactive glial scar tissue. These structures act as physical barriers, hindering electrical signal propagation and reducing neural implant functionality.

Development of three-layer collagen scaffolds to spatially direct tissue-specific cell differentiation for enthesis repair.

Enthesis repair remains a challenging clinical indication. Herein, a three-layer scaffold composed of a tendon-like layer of collagen type I, a fibrocartilage-like layer of collagen type II and a bone-like layer of collagen type I and hydroxyapatite, was designed to recapitulate the matrix composition of the enthesis. To aid tenogenic and fibrochondrogenic differentiation, bioactive molecules were loaded in the tendon-like layer or the fibrocartilage-like layer and their effect was assessed in setting using human bone marrow derived mesenchymal stromal cells and in an model.

The synergistic effect of physicochemical in vitro microenvironment modulators in human bone marrow stem cell cultures.

Modern bioengineering utilises biomimetic cell culture approaches to control cell fate during in vitro expansion. In this spirit, herein we assessed the influence of bidirectional surface topography, substrate rigidity, collagen type I coating and macromolecular crowding (MMC) in human bone marrow stem cell cultures. In the absence of MMC, surface topography was a strong modulator of cell morphology.

Photocatalytic generation of a non-heme Fe(iii)-hydroperoxo species with O in water for the oxygen atom transfer reaction.

Coupling a photoredox module and a bio-inspired non-heme model to activate O for the oxygen atom transfer (OAT) reaction requires a vigorous investigation to shed light on the multiple competing electron transfer steps, charge accumulation and annihilation processes, and the activation of O at the catalytic unit. We found that the efficient oxidative quenching mechanism between a [Ru(bpy)] chromophore and a reversible electron mediator, methyl viologen (MV), to form the reducing species methyl viologen radical (MV˙) can convey an electron to O to form the superoxide radical and reset an Fe(iii) species in a catalytic cycle to the Fe(ii) state in an aqueous solution. The formation of the Fe(iii)-hydroperoxo (Fe-OOH) intermediate can evolve to a highly oxidized iron-oxo species to perform the OAT reaction to an alkene substrate.

Assessing the combined effect of surface topography and substrate rigidity in human bone marrow stem cell cultures.

The combined effect of surface topography and substrate rigidity in stem cell cultures is still under-investigated, especially when biodegradable polymers are used. Herein, we assessed human bone marrow stem cell response on aliphatic polyester substrates as a function of anisotropic grooved topography and rigidity (7 and 12 kPa). Planar tissue culture plastic (TCP, 3 GPa) and aliphatic polyester substrates were used as controls.

Families in quarantine for COVID-19 in Italy. Resilience as a buffer of parental distress and problematic children's emotions and behaviors.

The pandemic of Covid-19 has had a high impact on people's lives and especially on families. In Italy, in 2020, the several forced closures led families to live indoors to manage anxiety and distress. It was considered appropriate to investigate which protective factors, like parental resilience, can mitigate the negative impact of pandemic-related distress on family life.

Heteroleptic Rare-Earth Tris(metallocenes) Containing a Dibenzocyclooctatetraene Dianion.

Isolable heteroleptic tris(metallocenes) containing five-membered and larger rings remain extremely scarce. The utilization of tripositive rare-earth-metal ions with ionic radii >1 Å allowed access to unprecedented and sterically congested dibenzocyclooctatetraenyl (dbCOT) metallocenes, [K(crypt-222)][CpRE(η-dbCOT)] (RE = Y (), Dy (); Cp = tetramethylcyclopentadienyl), through a salt metathesis reaction involving CpRE(BPh) and the potassium salt of the dbCOT dianion. The solid-state structures were investigated by single-crystal X-ray diffraction, magnetometry, and IR spectroscopy and provided evidence for the first crystallographically characterized (dbCOT) anion in a complex containing d- or f-block metals.

A combined physicochemical approach towards human tenocyte phenotype maintenance.

During culture, bereft of their optimal tissue context, tenocytes lose their phenotype and function. Considering that tenocytes in their native tissue milieu are exposed simultaneously to manifold signals, combination approaches (e.g.

Unfolding the innovation system for the development of countries: coevolution of Science, Technology and Production.

We show that the space in which scientific, technological and economic activities interplay with each other can be mathematically shaped using techniques from statistical physics of networks. We build a holistic view of the innovation system as the tri-layered network of interactions among these many activities (scientific publication, patenting, and industrial production in different sectors), also taking into account the possible time delays. Within this construction we can identify which capabilities and prerequisites are needed to be competitive in a given activity, and even measure how much time is needed to transform, for instance, the technological know-how into economic wealth and scientific innovation, being able to make predictions with a very long time horizon.

Coherent diversification in corporate technological portfolios.

We study the relationship between the performance of firms and their technological portfolios using tools borrowed from complexity science. In particular, we ask whether the accumulation of knowledge and capabilities associated with a coherent set of technologies leads firms to experience advantages in terms of productive efficiency. To this end, we analyze both the balance sheets and the patenting activity of about 70 thousand firms that have filed at least one patent over the period 2004-2013.