Construction and Validation of a risk model Based on Cuprotosis-related LncRNAsin Colon Adenocarcinoma.

Cancer cells are significantly impacted by copper-induced cell death (cuprotosis). Long noncoding RNAs (lncRNAs) are crucial in the developmental process of colon adenocarcinoma  (COAD). The ability of Cuprotosis-related lncRNA biomarkers to predict COAD prognosis, on the other hand, remains uncertain.

Fecal Microbiota Transplantation for the Treatment of Inflammatory Bowel Disease: An Update.

Fecal microbiota transplantation (FMT) has successfully been applied for the treatment of recurrent infection (CDI), which has led to studies on its application to other gastrointestinal diseases and extraintestinal diseases associated with gut microbiota dysbiosis. Recently, the results of FMT for patients with inflammatory bowel disease (IBD) have been encouraging. However, studies have not fully clarified the clinical application of this emerging therapy.

[Clinical study on FibroTouch and multi-parameter model for diagnosis of hepatic fibrosis in patients with chronic liver disease].

Objective: To explore the clinical application and related factors of FibroTouch in the diagnosis of liver fibrosis in patients with chronic liver disease through comparison of the specificity and sensitivity of FibroTouch and multi-parameter models, and to identify whether FibroTouch is a more accurate and safe method in diagnosis of liver fibrosis and evaluation of the therapeutic effect.

Methods: A total of 190 patients with chronic liver disease were performed liver biopsy and underwent liver stiffness measurement (LSM) using FibroTouch in department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University from January 2014 to February 2015. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (TBIL) were tested by enzymic method with automatic biochemistry analyzer.