Publications by authors named "Pu Yang"

Fermented Chinese Artichoke, a traditional Chinese fermented vegetable, has a distinctive flavor profile shaped by its fermentation process. This study applied flavoromics, metagenomics, and untargeted metabolomics to comprehensively analyze flavor compounds, microbial communities, and metabolic transformations during fermentation. We identified 43 volatile organic compounds (VOCs), with Terpineol, 1-Hexanol, and Linalool as the predominant components.

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Mg-modified biochar shows high adsorption performance under weakly acidic and neutral water conditions. However, its phosphate removal efficiency markedly decreases in naturally alkaline wastewater, such as that released in livestock farming (anaerobic wastewater with a high phosphate concentration). This research employed six machine learning models to predict and optimize the phosphate removal performance of bimetal-modified biochar (i.

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Cryptomonad phycoerythrin 545 (PE545) is an important type of phycobiliprotein in basic research and technological innovations. Herein, we report a minimalistic hydrophobic chromatography method for its purification. High purity was achieved, with a purity ratio (A/A) of 13.

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This study investigated the emulsifying and ethanol-induced gelling properties of capsicum pectins from bell pepper and chili pepper, and also examined the effect of deproteinization (using the Sevag method). The research revealed that bell pepper pectin (BPP) formed smaller aggregates (337 nm at pH 2) with a higher hydrophobicity in solution due to its lower molecular weight (2.02 × 10 g/mol) and higher degree of esterification (82.

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Background And Aims: The optimal management strategy for newly diagnosed pulmonary ground-glass nodules (GGNs) with suspected inflammatory etiology remains controversial in clinical practice. Empirical anti-inflammatory therapy is commonly used, but its efficacy compared with that of follow-up observation lacks high-quality evidence. Therefore, this study aims to compare the effectiveness of empirical anti-infective therapy and follow-up observation for pulmonary GGNs in real-world settings.

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Wound management has always been a challenge in the clinical treatment of diabetes. In this study, glucose oxidase (GOx) is grafted onto natural pullulan polysaccharides, and oxidization is carried out to form a self-healing hydrogel using carboxymethyl chitosan by means of reversible Schiff base covalent bonding. The smart-response drug release properties of this natural self-healing hydrogel are demonstrated in diabetic wounds by taking advantage of two key factors, namely the pH-responsive nature of Schiff base bonding and the fact that GOx reduces the pH in diabetic wounds.

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Article Synopsis
  • - A new bilayer moisture actuator was developed by combining cellulose fibers and chitosan, which enhances responsiveness and stability compared to traditional cellulose-based actuators.
  • - The strong electrostatic attraction between protonated chitosan and negatively charged cellulose nanofibrils allows for effective interfacial bonding and a wettability gradient, resulting in rapid moisture response.
  • - The actuator demonstrates impressive performance, with a bending angle of 60°, a 12-second response time, durability over 50 cycles, and potential applications in cooling textiles and artificial muscles.
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Harmful algal blooms (HABs) often occur in estuaries due to their unique environmental heterogeneity, posing significant environmental and human health risks. However, there is limited understanding of the community composition and community-level change points (thresholds) of harmful microalgae in subtropical estuaries. This study explored harmful microalgae community structure and thresholds in the Dafengjiang River estuary using a metabarcoding approach.

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  • - The study aimed to investigate how electroacupuncture (EA) affects the activation of astrocytes and the HMGB1/TLR4/MyD88 signaling pathway in rats with cervical spondylosis radiculopathy (CSR), to better understand its pain-relieving mechanisms.
  • - Twenty-four male SD rats were divided into four groups: blank, sham surgery, model, and EA, with the EA treatment applied to specific acupoints for 20 minutes daily over a week, followed by various assessments of pain and tissue samples for protein and cytokine analysis.
  • - Results showed that the model group had significant pain and inflammation markers compared to the sham group, with EA treatment helping to normalize some of these parameters, suggesting
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3D printing of a flexible polyurethane elastomer is highly demandable for its potential to revolutionize industries ranging from footwear to soft robotics thanks to its exceptional design flexibility and elasticity performance. Nevertheless, conventional methods like fused deposition modeling (FDM) and vat photopolymerization (VPP) polyurethane 3D printing typically limit material options to thermoplastic or photocurable polyurethanes. In this research, a water-borne polyurethane ink was synthesized for direct ink writing (DIW) 3D printing through the incorporation of cellulose nanofibrils (CNFs), enabling direct printing of complex, monolithic elastomeric structures at room temperature that can maintain the designed structure.

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Indole and skatole (3-methylindole, CHN) are common nitrogen-containing heterocyclic pollutants found in waste, wastewater treatment plants, and public restrooms and are the most notorious compounds in animal feces. Biodegradation was considered a feasible method for the removal of indole and skatole, but a comprehensive understanding of the metabolic pathways under both aerobic and anaerobic conditions was lacking, and the functional genes responsible for skatole biodegradation remained a mystery. Through metagenomic and gene cluster functional analysis, p38 (NCBI: CP167896), (styrene monooxygenase: ACDW34_08180), and (styrene monooxygenase: ACDW34_08350) were identified as having the potential to degrade indole and skatole.

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  • Chinese Baijiu is a well-known alcoholic drink from China, and this study focuses on the interactions between key microorganisms during its fermentation at different temperatures.
  • Results showed that one microorganism significantly reduced the growth and lactic acid production of another when the temperature was above 15 °C, while the first microorganism did not affect the growth of a third microorganism involved in ethanol production.
  • A detailed analysis revealed that key enzymes for sugar metabolism and lactic acid production were less active in the presence of the dominant microorganism, highlighting its inhibitory role and offering insights for optimizing Baijiu fermentation processes.
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Deoxyribonucleotide (DNA) is uniquely programmable and biocompatible, and exhibits unique appeal as a biomaterial as it can be precisely designed and programmed to construct arbitrary shapes. DNA hydrogels are polymer networks comprising cross-linked DNA strands. As DNA hydrogels present programmability, biocompatibility, and stimulus responsiveness, they are extensively explored in the field of biomedicine.

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Skeletal muscle satellite cells (SMSCs), a type of myogenic stem cell, play a pivotal role in postnatal muscle regeneration and repair in animals. Circular RNAs (circRNAs) are a distinct class of non-coding RNA molecules capable of regulating muscle development by modulating gene expression, acting as microRNAs, or serving as protein decoys. In this study, we identified circ_14820, an exonic transcript derived from adenosine triphosphatase family protein 2 (ATAD2), through initial RNA-Seq analysis.

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Recent advancements in the application of lipid biomarkers as paleoenvironmental indicators have provided invaluable insights into the dynamics of climatic variations, vegetative histories, and anthropogenic impacts. However, our current understanding of nitrogen-containing lipid biomarkers (NCLBs) in sedimentary deposits remains limited, notwithstanding their potential significance in global nitrogen cycling. To bridge this research gap, a comprehensive study was conducted to characterize the distribution patterns of n-alkyl amides (NAAs) and n-alkyl nitriles (NANs) in representative paleo-lake and loess sedimentary profiles from the arid region of northwestern China (NWC).

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Phycocyanin 620 (PC620) is the outermost light-harvesting complex in phycobilisome of cyanobacteria, engaged in light collection and energy transfer to the core antenna, allophycocyanin. Recently, long-lived exciton-vibrational coherences have been observed in allophycocyanin, accounting for the coherent energy transfer [Zhu et al., Nat.

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Article Synopsis
  • Post-translational modifications (PTMs) are essential for regulating the function and stability of proteins, particularly the tumor suppressor PTEN, which is important in controlling cellular processes like growth and survival.
  • PTEN is commonly dysregulated in cancers, and its modifications such as phosphorylation, acetylation, and SUMOylation can impact its activity, stability, and interactions with other proteins.
  • Exploring PTMs of PTEN may lead to new therapeutic strategies for cancer treatment by potentially restoring its tumor-suppressing functions, beyond current methods that mainly target the PI3K pathway.
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Background: A stent with characteristics of a hybrid design may have advantages in improving the patency of symptomatic iliofemoral vein obstruction. This study assessed the safety and effectiveness of the V-Mixtent Venous Stent in treating symptomatic iliofemoral outflow obstruction.

Methods: Eligible patients had a Clinical-Etiologic-Anatomic-Physiologic (CEAP) C classification of ≥ 3 or a Venous Clinical Severity Score (VCSS) pain score of ≥ 2.

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Background And Aims: Thromboangiitis obliterans (TAO), also known as Buerger's disease, is a rare vasculitis. Observational epidemiology studies have suggested a relationship between the gut microbiota and TAO. However, due to confounding factors and reverse causality, the causal relationship remains unclear.

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  • Lung cancer (LC) is the leading cause of cancer-related deaths in China, with the study analyzing its trends and risk factors from 1990 to 2019 and projecting the next 41 years.
  • Data collected on lung cancer incidence, deaths, and disability-adjusted life years (DALYs) revealed that all three metrics increased over the studied period, with specific risk factors like ambient particulate matter pollution showing significant rises while some factors like household air pollution decreased.
  • An autoregressive integrated moving average (ARIMA) model predicts continued increases in mortality and DALYs rates due to lung cancer, suggesting an ongoing escalation in the disease's burden in China.
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Lignocellulosic nanofibrils (LCNFs) isolation is recognized as an efficient strategy for maximizing biomass utilization. Nevertheless, achieving a 100% yield presents a formidable challenge. Here, an esterification strategy mediated by the equilibrium moisture in biomass is proposed for LCNFs preparation without the use of catalysts, resulting in a yield exceeding 100%.

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Background: Electronic symptom monitoring via patient-reported outcomes in surgical oncology is limited owing to lengthy instruments and non-specific items in common patient-reported outcome instruments. To establish electronic symptom monitoring through a clinically relevant and fit-for-purpose core set of patient-reported outcome in patients undergoing lung cancer surgery.

Materials And Methods: One qualitative (Cohort 1) and two prospective studies (Cohorts 2 and 3) were conducted between 2018 and 2022.

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Article Synopsis
  • - The study focused on SiMBR genes in foxtail millet, identifying ten specific genes that play a role in drought stress responses and analyzing their structural features and regulatory elements.
  • - SiMBR2, a gene linked to drought tolerance, was shown to improve drought resistance when expressed in Arabidopsis by lowering reactive oxygen species levels during water deficit.
  • - Overall, the research highlights the potential of SiMBR genes in foxtail millet to enhance genetic resilience in other crops, offering insights into drought tolerance mechanisms for future breeding efforts.
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