Publications by authors named "Prunelle Getten"

Although anti-severe acute respiratory syndrome-coronavirus 2 antibody kinetics have been described in large populations of vaccinated individuals, we still poorly understand how they evolve during a natural infection and how this impacts viral clearance. For that purpose, we analyzed the kinetics of both viral load and neutralizing antibody levels in a prospective cohort of individuals during acute infection with alpha variant. Using a mathematical model, we show that the progressive increase in neutralizing antibodies leads to a shortening of the half-life of both infected cells and infectious viral particles.

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Article Synopsis
  • - The objective of the study is to evaluate how psychosocial risk factors contribute to the increased use of emergency hospital services by patients with sickle cell disease.
  • - The review will include all original quantitative studies without language restrictions that look at the impact of these psychosocial factors on emergency hospital visits for sickle cell patients.
  • - A systematic search of multiple databases will be conducted, with two authors independently selecting studies and extracting data, while assessing study quality and potentially performing meta-analyses to analyze the findings.
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