Comparison of total blood loss between limited tourniquet use and conventional tourniquet use in total knee arthroplasty: a randomized controlled trial.

Background: This study examined the differences in total blood loss, the need for blood transfusions, length of hospital stay, wound grading scores, incidence of venous thromboembolism (VTE), and reoperation rates between conventional and limited tourniquet use during unilateral primary total knee arthroplasty (TKA).

Methods: This double-blind, randomized controlled trial included 90 patients undergoing unilateral primary TKA. Forty-five patients were allocated to the limited tourniquet use group (LIM-TKA), and 45 to the conventional tourniquet use group (CON-TKA).

Coronal plane stability of cruciate-retaining total knee arthroplasty in valgus gonarthrosis patients: A mid-term evaluation using stress radiographs.

Background: Total knee arthroplasty (TKA) using implants with a high level of constraint has generally been recommended for patients with osteoarthritis (OA) who have valgus alignment. However, studies have reported favorable outcomes even with cruciate-retaining (CR) implants.

Aim: To evaluate the coronal plane stability of CR-TKA in patients with valgus OA at the mid-term follow-up.

Complete Release of the Superficial Medial Collateral Ligament in Total Knee Arthroplasty.

Background: Proper soft-tissue balance was essential in total knee arthroplasty (TKA). Superficial medial collateral ligament (sMCL) release has been recommended in correction of severe varus knee. However, it has concerns of overcorrection.

Posterior Cruciate Ligament Resection and Varus Correction in Total Knee Arthroplasty: A Study Using Computer-Assisted Surgery.

Background: Alignment correction is crucial for sustaining longevity and function in total knee arthroplasty (TKA). Although the posterior cruciate ligament (PCL) is a secondary stabilizer in the coronal plane, there have been few reports on the effects of PCL resection on varus correction. The study aim was to assess the effect of PCL resection performed using computer-assisted surgery (CAS) on varus correction in TKA.

Debridement, antibiotics, and implant retention combined with direct intra-articular antibiotic infusion in patients with acute hematogenous periprosthetic joint infection of the knee.

Background: Debridement, antibiotics, and implant retention (DAIR) is the recommended treatment for acute hematogenous periprosthetic joint infection (PJI) after total knee arthroplasty (TKA). However, DAIR is associated with a high percentage of unsuccessful outcomes. Since 2007, direct intra-articular antibiotic infusion, which can provide a high concentration of intra-articular antibiotic, has been used in combination with DAIR to improve treatment outcomes among patients in our institution.

Randomized Double-Blind Controlled Trial Comparing 0.2 mg, 0.1 mg, and No Intrathecal Morphine Combined With Periarticular Injection for Unilateral Total Knee Arthroplasty.

Background: The addition of intrathecal morphine (ITM) to neuraxial anesthesia during total knee arthroplasty (TKA) to achieve postoperative analgesia can elicit opioid-related side effects. The other methods of pain alleviation and side effect reduction, including multimodal analgesia, are challenging. This study aimed to determine the efficacy of various ITM dosages for primary unilateral TKA with periarticular injection (PI).

Results of peri-articular steroid injection in the treatment of chronic extra-articular pain after total knee arthroplasty.

Objective: The authors conducted study to analyze results of peri-articular steroid injection in the treatment of chronic pain from soft tissue inflammation after total knee arthroplasty (TKA).

Material And Method: The authors retrieved data from all patients underwent TKA whom suffered with chronic extra-articular pain and received local peri-articular steroid injection by 2 senior authors during January 1, 2008 to June 30, 2010. Clinical evaluation such as pain score, knee score and functional score were recorded pre-injection and three months after injection.

Computer assisted surgery evaluation of femoral component rotation in well-balanced and well-aligned total knee arthroplasty using gap technique.

Objective: Using computer assisted surgery (CAS) to assess femoral component rotation in well-balanced, well-aligned total knee arthroplasty (TKA) implanted with Posterior Cruciate Ligament (PCL) excision type prosthesis using gap technique.

Material And Method: Using CAS, well-balanced TKA was defined by both flexion/extension and medial/lateral gap difference of less than 2 mm and well-aligned TKA was defined by final mechanical axis within +/- 3 degrees deviation and flexion contracture of less than 5 degrees without hyper extension. Femoral component rotation was determined by posterior condylar axis versus proximal tibia resection plane.

Effects of posterior cruciate ligament resection in total knee arthroplasty using computer assisted surgery.

Objective: The authors prospectively measure the effects of Posterior Cruciate Ligament (PCL) excision in Total Knee Arthroplasty (TKA) using Computer Assisted Surgery (CAS).

Material And Method: Between April 2008 and June 2008, sixteen knees of fifteen patients with varus deformity less than 20 degree and grossly intact PCL were included in this study. Using CAS and tensioning device to maintain consistent pressure, extension and flexion gap on both medial and lateral side before and after resection of PCL was recorded.

A comparison of early clinical outcome in computer assisted surgery and conventional technique in minimally invasive total knee arthroplasty.

Objective: To compare the clinical outcomes of minimally invasive total knee arthroplasty (MIS TKA) with and without computer assisted surgery (CAS).

Material And Method: From September 2007 to February 2008, 64 patients (70 knees) underwent MIS TKA were included. Clinical data such as operative time, pain score, total blood loss and Radiographic data were recorded and compared.

NF-kappaB p65 involves in reperfusion injury and iNOS gene regulation in skeletal muscle.

This study investigated the effects of inhibition of NF-kappaB activation on microcirculation and inducible NOS expression in reperfused rat cremaster muscle. The muscle from 16 rats underwent 5-h ischemia and 90-min reperfusion. Each rat received NF-kappaB inhibitor pyrrolidine dithiocarbamate (PDTC, 150 mg/kg) or phosphate-buffered saline 15 min before reperfusion.