Objective: While up to 35% of children with asthma have evidence of sleep disordered breathing (SDB), it is unclear if nocturnal symptoms stem from asthma itself or SDB. The Pediatric Sleep Questionnaire (PSQ) is a validated tool for identifying SDB in childhood asthma. We hypothesize children with asthma and abnormal PSQ demonstrate decreased asthma control and are at higher risk of obstructive sleep apnea (OSA).
View Article and Find Full Text PDFUp to 80% of asthmatic children may experience upper airway symptoms which are often perceived as coming from the lower airways. Currently, there are no validated questionnaires to assess upper airway contribution to pediatric asthma symptoms. The Sino-Nasal 5 (SN-5) questionnaire was previously validated for identifying radiographic confirmed sinus disease in children.
View Article and Find Full Text PDFThe dissolution and bioavailability of etodolac from capsules exposed to high relative humidity and temperature were compared to those from capsules stored at room temperature (RT). Dissolution of stressed and control capsules was evaluated using a USP basket apparatus at 100 rpm with 900 mL pH 7.5 phosphate buffer (0.
View Article and Find Full Text PDFJ Stud Alcohol
September 1992
The role of self-efficacy in the prediction of relapse following alcoholism treatment was examined in a 12-month follow-up evaluation. Self-efficacy was assessed at intake to inpatient treatment and again at discharge. The drinking status of male alcoholics completing treatment then was assessed during six intervals over the course of the posttreatment year.
View Article and Find Full Text PDFThe utility of disulfiram in the treatment of alcohol abuse has been limited by the high frequency with which clients refuse the regimen. The present study identified variables influencing disulfiram acceptance/rejection within the framework of the theory of reasoned action. Eighty male inpatients on an alcohol treatment unit completed a questionnaire operationalizing the components of the model.
View Article and Find Full Text PDFIn an inpatient alcoholism rehabilitation program, 56 men were administered two 10-min memory tests: the Product Recall Test (PRT), designed to assess memory for familiar stimuli (assumed to be relatively high in ecological relevance), and the Memory-for-Designs Test (MFD), a test of memory for novel patterns of stimuli (assumed to be relatively low in ecological relevance). Approximately 74% of subjects who recalled less than or equal to half the items of the PRT relapsed at 3 months compared to only 33% of the subjects who recalled more than half the items. Performance on the MFD was not related to relapse rate.
View Article and Find Full Text PDFThe present study represents a long-term follow-up of elderly persons who completed a behavioral treatment program for alcohol problems. Subjects over the age of 60 at the time they obtained treatment for alcohol abuse were contacted two to four years after discharge. Interviews with the alcohol abuser and a significant other were conducted in an effort to identify the percentage of persons for whom treatment had sustained beneficial effects, differences in outcome for early-versus late-onset alcohol abusers, and demographic and daily activity variables that distinguish abstinent from nonabstinent individuals.
View Article and Find Full Text PDFThe effect of an appointment-keeping intervention on attendance at aftercare was examined for 50 male participants in an inpatient alcohol treatment program. Subjects received either a calendar prompt and home-based attendance contract intervention (Experimental group, N = 25) or standard aftercare treatment arrangements (Control group, N = 25). Participants were followed for eight aftercare sessions over a 6-month period.
View Article and Find Full Text PDFA high-performance liquid chromatographic (HPLC) method for the simultaneous determination of pralidoxime chloride (I) and its major decomposition products in an injectable formulation is described. I and its decomposition products were detected and quantitated by their UV absorbances at 270 nm, after being separated from related compounds and formulation excipients on a reverse-phase C-18 column using a mobile phase consisting of 52% acetonitrile and 48% of an aqueous solution containing 0.005 M phosphoric acid and 0.
View Article and Find Full Text PDFA three-study series was conducted to examine smoking topography across clinical, laboratory, and naturalistic settings for 24 smokers who were patients in an alcohol treatment program. Experiments 1 and 2 included surreptitious observation of smoking in group therapy sessions (naturalistic), and obtrusive observation of smoking in a smoking clinic setting. The third study added a laboratory smoking condition to the clinic and group conditions.
View Article and Find Full Text PDFAn abbreviated breath test for detecting the disulfiram metabolite carbon disulfide (CS2) was evaluated in an analogue investigation of the sensitivity of the test in identifying disulfiram and non-disulfiram intake in a group of 14 alcoholic inpatients. Disulfiram (250 mg) was administered within an ABAB repeated measures design over a 12-day period with corresponding breath tests administered during morning and afternoon time periods. Dependent measures included spectrophotometric analysis of reacted test samples and visual ratings of sample color.
View Article and Find Full Text PDFAddict Behav
February 1984
Self-help methods are preferred by smokers over clinic-based treatments providing more traditional services. Unfortunately, these more popular methods have not been extremely successful in getting smokers to quit. The poor success rates may be partially related to the lack of structure inherent in these treatment approaches.
View Article and Find Full Text PDFAftercare to prevent relapse following alcohol treatment has not received adequate experimental investigation. The present study monitored alcohol intake of 50 patients following assignment to either an intensive aftercare recruitment procedure or regular clinic aftercare. The results indicated that those who received the intensive aftercare procedure showed delayed relapse.
View Article and Find Full Text PDFThe reactive effects of three self-monitoring procedures were evaluated with respect to compliance with the self-monitoring requirements and session attendance. A total of 50 smokers who agreed to participate in a smoking cessation program were randomly assigned to one of five conditions: three self-monitoring conditions and two no self-monitoring control conditions. Results indicate that groups were initially equal on the variables of age, sex, pack year history, estimated rate of consumption, and alveolar carbon monoxide level.
View Article and Find Full Text PDFJ Behav Ther Exp Psychiatry
March 1981
End stage renal disease is the most severe stage of kidney failure. Hemodialysis or kidney transplants are required to insure patient survival. When dialysis treatment is used, patients experience dietary restrictions and consequently must limit fluid and food intake to compensate for the lack of kidney functioning.
View Article and Find Full Text PDFCommunity Ment Health J
December 1979
Recent reserach has examined variables related to attendance of aftercare services because of the correlation between aftercare and posthospitalization treatment success. The present study, which examined aftercare attendance for 40 randomyl selected subjects following discharge from an inpatient alcohol treatment program, extends the list of variables found to influence attendance. A multiple-regression analysis of subject demographic variables and variables of a more programmatic nature found that distance variables (e.
View Article and Find Full Text PDFJ Assoc Off Anal Chem
November 1977
A gas-liquid chromatographic (GLC) method is described for determining isosorbide dinitrate (ISDN) in tablets. ISDN is extracted from tablet excipients by a 2-phase system composed of water-ethyl ether, and detected and quantitated with a flame ionization detector after separation from the internal standard (glyceryl tributyrate) on a 3% OV-210 column. Ten replicate assays on 2 different batches of tablets, each containing 5 mg ISDN, gave coefficients of variation of 1.
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