Polysaccharide Composite Alginate-Pectin Hydrogels as a Basis for Developing Wound Healing Materials.

This article presents materials that highlight the bioengineering potential of polymeric systems of natural origin based on biodegradable polysaccharides, with applications in creating modern products for localized wound healing. Exploring the unique biological and physicochemical properties of polysaccharides offers a promising avenue for the atraumatic, controlled restoration of damaged tissues in extensive wounds. The study focused on alginate, pectin, and a hydrogel composed of their mixture in a 1:1 ratio.

[Acute coronary syndrome: modern approaches to diagnosis and treatment].

Diseases of blood circulatory system for a long time are very widespread and stay being the main course of mortality in Russian Federation. The article presents a short review of methods of treatment in conditions of instable stenocardia and myocardial infarction, principles of theirs using and results of treatment in hospitals.

[Cerebro-cardial disorders in hemorrhagic stroke].

Aim: To elucidate relationships brain-heart in hemorrhagic stroke depending on the size and location of hematoma and initial state of the heart.

Material And Methods: Clinical and paraclinical methods were used in acute and rehabilitation periods in 160 patients with hemorrhagic stroke.

Results: Symptoms of cerebrocardial syndrome in hemorrhagic stroke include arrhythmias (tachycardia, bradycardia, extrasystole, cardiac fibrillation, sick sinus syndrome), blocks (transient bundle-branch block), myocardial dystrophy, in IHD--ischemic myocardial disorders up to subendocardial myocardial infarction.

[The identification investigation of the material evidence of biological origin after multifactorial exposure].

The possibility of investigating pieces of material evidence of biological origin after exposure to various factors is evaluated. The possibility of detecting proteins of liquid media of human organism by electrophoresis in polyacrylamide denatured gel is investigated. The method is intended for identification of biological material in a state of grave destruction.

[Establishing the personal identity of the victims in aviation catastrophes].

Algorithm of organization measures and expert investigations is proposed, based on experience gained in expert studies during liquidation of aircraft catastrophes. It permits effective classification, differentiation, and identification of victims and is based on traditional and high technological methods of investigation.

[The characteristics of the morphological changes to the parenchymatous organs in persons who used street narcotics].

Morphologic signs of narcomania in subjects using primitively prepared narcotics from opium-containing raw material are described. Sites of injections and inflammatory reactions in the parenchymatous organs are described. Special attention is paid to productive hypersensitive inflammation, which can serve as a sign confirming narcomania in subjects using poorly purified narcotic mixture.

[Hemostasis and antithrombotic therapy in massive thromboembolism of pulmonary artery].

The results of treatment are reviewed for 114 patients with massive thromboembolism of the pulmonary artery in respect to antithrombolytic measures and initial condition of hemostasis. Prognostic hemostasiological criteria of tolerance and relative resistance of the patients to streptokinase preparations and optimal thrombolytic methods in massive thromboembolism of the pulmonary artery are determined.

[The neurological aspects of chromaffinoma].

Vegetative dysfunction with episodes of tachycardia, hypertension, paleness, general hyperhidrosis, subfebrile condition, hyperglycemia manifest first among clinical symptoms of chromaffinoma. In respect to these symptoms severity the crises observed in chromaffinoma are classified as minor or major. Major crises may be cerebral, epileptiform, cardial and abdominal.

[Somatogenic toxic-circulatory encephalopathies with pseudotumorous course].

A progredient course of cerebral circulatory disorders in grave-condition somatic patients may present a clinical picture of toxic dyscirculatory encephalopathy with brain symptoms of mass lesions. Pseudotumorous run of a chronic vascular process requires a sound clinical analysis and adjuvant methods of examination to rule out primary tumor or brain metastases.

[Status of microcirculation in patients with ischemic heart disease and concomitant bronchopulmonary diseases].

Microcirculation was studied by bulbar biomicroscopy in 111 coronary patients (105 males and 6 females) treated at sanatorium. Eighty-three of them exhibited concomitant bronchopulmonary impairment: chronic obstructive, chronic nonobstructive bronchitis and bronchial asthma in 40, 36 and 7 patients, respectively. The combined effect of the diseases leading to mutual aggravation has an adverse sequelae in terminal circulation, which can be managed by therapeutic impact on cardiorespiratory system.

[The status of the nervous system in mechanical jaundice].

In mechanical jaundice there may arise two kinds of CNS abnormalities: light disorders consistent with clinical signs of the underlying disease and neurological complications such as encephalopathy, encephalomyelopathy, polyneuropathies, neurasthenia. Neurological disorders are attributed mainly to initial severe autotoxication as well as hemodynamic affections. Of importance are also other risk factors (premorbid personality traits, advanced age, etc.

[Diagnosis and treatment of chronic spinal arachnoiditis].

Altogether 61 patients with chronic spinal arachnoiditis underwent clinical and laboratory studies for deranged functions of the nervous system. The main neurologic syndromes, the results of examining cerebrospinal fluid and spondylo- and myelography data are given. At the first stage the treatment should be conservative.

[Cholestatic toxic-vascular encephalopathy and encephalomyelopathy].

Patients with mechanical jaundice showed signs of organic lesions of the nervous system: the syndrome of cholestatic encephalopathy (n = 56) and encephalomyelopathy (n = 9). Pathomorphological disorders are presented in the form of toxico-hypoxic changes of the neural cells and neuroglia in combination with organic changes in the vascular wall and functional disturbances of the blood flow and the cerebrospinal fluid dynamics. It is suggested that marked autointoxication and hemodynamic disturbances play the leading role in the pathogenesis of neurological disorders in mechanical jaundice.