Publications by authors named "Prokudin V"

Based on the principles of rehabilitation elaborated by M.M. Kabanov (partnership, multidirectional nature and intergrity of psychosocial efforts), the authors have worked out a model of a complex team (neurologist, psychiatrist, psychotherapist and all medical personnel of the neurological unit) biopsychosocial approach to early psychosocial rehabilitation of patients who survived acute) ischemc attack.

View Article and Find Full Text PDF
[Psychiatric service in general hospital].

Zh Nevrol Psikhiatr Im S S Korsakova

May 2002

The article summarizes the 3-year (1998-2000) consulting and treatment experience of a psychotherapeutic unit in one Moscow general hospital. Psychiatrists realized emergent and planned consultations of the mentally-ill patients in all hospital departments, conducted, in addition to general treatment, psychopharmacotherapy and psychotherapy or directed them, on demand, to psychiatric hospitals. For the 3-year period, the psychiatrists have consulted 4685 somatic patients with comorbid mental diseases (5% of the total amount of the patients admitted to the hospital at that period), 1360 patients (29%) being affected with psychotic disorders.

View Article and Find Full Text PDF
[Psychotherapeutic service in general somatic hospital].

Zh Nevrol Psikhiatr Im S S Korsakova

October 2001

The paper presents the experience of the activity of psychotherapeutic department in general somatic hospital during 3 years. For this period specialists of this department (psychotherapist, psychiatrist, medical psychologist and a nurses) were consulted 4528 patients. Some disorders of nonpsychotic level were found in 2915 cases.

View Article and Find Full Text PDF

A hypnotic effect of chalcion (triazolam) was studied in 24 outpatients suffering from insomnia. It was found high and beneficial in pre-, intra- and post-insomniac disorders. Side effects were mild.

View Article and Find Full Text PDF

The inhibitory effect of adenosine on aggregation of human platelets activated by platelet activating factor (PAF), ADP and serotonin (5-HT) were examined using native platelets from blood of volunteers. Platelet aggregation was determined by Born's method. Effective adenosine concentrations (IC50) which had inhibited platelet aggregation were found to be 0.

View Article and Find Full Text PDF

The content of purine compounds in red blood cells was measured and compared in 21 neonates with a history of chronic intrauterine hypoxia, depending on the condition at birth and the early period of adaptation. The content of purine compounds in whole blood was measured at the moment of birth and on days 1, 3 and 5 of life. It has been disclosed that the pattern of purine metabolism abnormality in funic red blood cells makes it possible to predict the course of the early period of adaptation.

View Article and Find Full Text PDF

The distribution of purine compounds in the skeletal muscles of the anterior and posterior limbs of 129/Re mice with hereditary muscular dystrophy (HMD) was investigated in a comparative study. The results revealed unidirectional metabolic disorders in both groups of muscles which was manifested in a quantitative redistribution of phosphorus-containing purine components and a decrease in the pool of adenylates in muscle tissue. Elevated concentrations of purine metabolites (inosine, hypoxanthine, xanthine, and uric acid) indicated an augmented metabolism of purines in this abnormality.

View Article and Find Full Text PDF
Article Synopsis
  • The study examined how purine metabolism is affected in the skeletal muscles of 129 Re mice with hereditary muscular dystrophy, finding lower ATP levels and higher levels of AMP, IMP, and uric acid.
  • There were no significant changes in the purine nucleotide pool in red blood cells, but physical properties of these cells showed reduced pliability and altered temperature resistance at 50 degrees Celsius.
  • The observed changes in the erythrocytes' physical properties are linked to issues in the contractile structure beneath their membranes, suggesting a connection to the muscular dystrophy condition.
View Article and Find Full Text PDF

For 10-15 years the authors studied the time-course of neurosis-like disturbances in 46 patients with schizophrenia manifested in adolescence with cenesthopathic symptomatology (23 patients presented the cenesthopathic-hypochondriac syndrome, in 17 cenesthopathia was attended by phobias, in 6 it was combined with manifestations of derealization and depersonalization). The study showed that in 87% of the observations the disease ran continuously (torpidly in 29, by the type of the simple form in 5 and by the type of the paranoid form in 6 patients), in 13% of the patients the disease ran a paroxysm-progressive course. In 10-15 years the clinical picture in half of the patients continued to be characterized by the leading cenestho-hypochondriac symptomatology, in one-fourth of patients cenestho-hypochondriac disturbances were transformed into hallucinational-paranoid, in another one-fourth of patients into either psychosis-like or apathoabulic (by the type of the simple form) symptomatology.

View Article and Find Full Text PDF

A clinico-statistical analysis covers 825 psychotic patients who applied to the Amanuel mental hospital in Addis-Abeba over the first 3 months of 1983. The population of patients had the following characteristics associated with cultural factors: a considerable predominance of males, a dramatic reduction in the number of both male and female patients with an increasing distance between their place of residence and the hospital, a large percentage of non-working individuals, single men and divorced women. Among the entire number of mental patients primary patients constituted 67.

View Article and Find Full Text PDF