Publications by authors named "Projesh Kumar Roy"

The main cause of the fragile-to-strong crossover of 3D silica was previously attributed to the presence of a low-energy cutoff in the potential energy landscape. An important question emerges about the microscopic origin of this crossover and its generalizibility to other glass-formers. In this work, the fragile-to-strong crossover of a model two-dimensional (2D) glassy system is analyzed via molecular dynamics simulation, which represents 2D-silica.

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The violation of the Pauli principle has been surmised in several models of the fractional exclusion statistics and successfully applied to several quantum systems. In this paper, a classical alternative of the exclusion statistics is studied using the maximum entropy methods. The difference between the Bose-Einstein statistics and the Maxwell-Boltzmann statistics is understood in terms of a separable quantity, namely the degree of indistinguishability.

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Using extensive molecular dynamics simulations, we investigate the slowdown of dynamics in a 3D system of ring polymers by varying the ambient pressure and the stiffness of the rings. Our study demonstrates that the stiffness of the rings determines the dynamics of the ring polymers, leading to glassiness at lower pressures for stiffer rings. The threading of the ring polymers, a unique feature that emerges only due to the topological nature of such polymers in three dimensions, is shown to be the determinant feature of dynamical slowdown, albeit only in a certain stiffness range.

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Background And Study Aims: The pathogenesis of functional dyspepsia (FD) is complex and still remains to be established. Recent studies support duodenal inflammation with increased infiltration of eosinophils and a higher level of systemic cytokines among patients with FD. These findings may help to understand the underlying pathophysiology of FD.

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The thermodynamic properties of subsystems in strong interaction with the neighborhood can largely differ from the standard behavior. Here we study the thermodynamic properties of rings and triplets in equilibrated disordered 2D silica. Their statistics follows a Boltzmann behavior, albeit with a strongly reduced temperature.

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Recently, it became possible to experimentally generate and characterize a very thin silica system on a substrate which can be basically described as a 2D random network. The key structural properties, in particular related to the ring statistics, could be numerically reproduced by performing molecular dynamics simulations with an appropriately chosen 2D force field. Using a maximum entropy formulation it is shown that the probability distribution of the individual rings and triplets can be related to the ring and triplet energies, respectively, obtained from the simulations.

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The recent experimental discovery of a semi two-dimensional silica glass has offered a realistic description of the random network theory of a silica glass structure, initially discussed by Zachariasen. To study the structure formation of silica in two dimensions, we introduce a two-body force field, based on a soft core Yukawa potential. The different configurations, sampled via Molecular dynamics simulations, can be directly compared with the experimental structures, which have been provided in the literature.

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Aim: Diabetes mellitus (DM) represents one of the major lifestyle-related pathological conditions; the incidence and prevalence of DM have reached an epidemic level around the world. Diabetes mellitus is usually associated with obesity, coronary diseases, and cerebral pathologies. However, more insights are required to evaluate a temporal relation between DM and hepatic functions.

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The prognosis of decompensated cirrhosis of liver resulting from chronic Hepatitis B Virus (HBV) infection is poor and liver transplantation is the only established mode of treatment. The benefits of treatment with interferon are outweighed by serious side effects and risks of fatal exacerbation of disease activity. Lamivudine rapidly reduces hepatitis B viral DNA in serum to undetectable levels.

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