Automatic localisation and per-region quantification of traumatic brain injury on head CT using atlas mapping.

Rationale And Objectives: To develop a method for automatic localisation of brain lesions on head CT, suitable for both population-level analysis and lesion management in a clinical setting.

Materials And Methods: Lesions were located by mapping a bespoke CT brain atlas to the patient's head CT in which lesions had been previously segmented. The atlas mapping was achieved through robust intensity-based registration enabling the calculation of per-region lesion volumes.