Pollinator functional group abundance and floral heterogeneity in an agroecological context affect mating patterns in a self-incompatible wild plant.

Premise: Restoration of seminatural field margins can elevate pollinator activity. However, how they support wild plant gene flow through interactions between pollinators and spatiotemporal gradients in floral resources remains largely unknown.

Methods: Using a farm-scale experiment, we tested how mating outcomes (expected heterozygosity and paternity correlation) of the wild, self-incompatible plant Cyanus segetum transplanted into field margins (sown wildflower or grass-legume strips) were affected by the abundance of different pollinator functional groups (defined by species traits).

Long-term cattle grazing shifts the ecological state of forest soils.

Cattle grazing profoundly affects abiotic and biotic characteristics of ecosystems. While most research has been performed on grasslands, the effect of large managed ungulates on forest ecosystems has largely been neglected. Compared to a baseline seminatural state, we investigated how long-term cattle grazing of birch forest patches affected the abiotic state and the ecological community (microbes and invertebrates) of the soil subsystem.

Pathways for Novel Epidemiology: Plant-Pollinator-Pathogen Networks and Global Change.

Multiple global change pressures, and their interplay, cause plant-pollinator extinctions and modify species assemblages and interactions. This may alter the risks of pathogen host shifts, intra- or interspecific pathogen spread, and emergence of novel population or community epidemics. Flowers are hubs for pathogen transmission.

The functional role of temperate forest understorey vegetation in a changing world.

Temperate forests cover 16% of the global forest area. Within these forests, the understorey is an important biodiversity reservoir that can influence ecosystem processes and functions in multiple ways. However, we still lack a thorough understanding of the relative importance of the understorey for temperate forest functioning.

Notes on some enigmatic taxa of limnoterrestrial rhabdocoels, with the description of two new species.

Six taxa of limnoterrestrial rhabdocoels are discussed, two of them, both belonging to Typhloplanidae Graff, 1905, are new to science. Adenoplea reisingeri n. sp.

Revision of Acrochordonoposthia Reisinger, 1924 (Rhabditophora, Typhloplanidae, Protoplanellinae) with the description of one new species.

An overview of the morphology, taxonomy and distribution of all known species of the rhabdocoel taxon Acrochordonoposthia is provided. One new species A. vandeputae n.

A novel mutation in the complement regulator clusterin in recurrent hemolytic uremic syndrome.

A novel heterozygous mutation in the clusterin gene, nucleotide position A1298C (glutamine>proline Q433P), was detected in exon 7 of a child with recurrent hemolytic uremic syndrome (HUS). The same mutation was found in the child's two siblings and mother but not in 120 controls. In addition, a previously described heterozygous mutation was detected in the gene encoding membrane cofactor protein (MCP) causing a 6 base-pair deletion 811-816delGACAGT in exon 6.

Nail-patella syndrome, infantile nephrotic syndrome: complete remission with antiproteinuric treatment.

A girl, second child of healthy parents, was referred to the Renal Unit at the age of 9 months with haematuria (230 RBC/microl) and proteinuria (2.4 g/l). Serum creatinine was normal (0.

GNAS defects identified by stimulatory G protein alpha-subunit signalling studies in platelets.

Context: GNAS is an imprinted region that gives rise to several transcripts, antisense transcripts, and noncoding RNAs, including transcription of RNA encoding the alpha-subunit of the stimulatory G protein (Gsalpha). The complexity of the GNAS cluster results in ubiquitous genomic imprints, tissue-specific Gsalpha expression, and multiple genotype-phenotype relationships. Phenotypes resulting from genetic and epigenetic abnormalities of the GNAS region include Albright's hereditary osteodystrophy, pseudohypoparathyroidism types Ia (PHPIa) and Ib (PHPIb), and pseudopseudohypoparathyroidism (PPHP).

The neurogenic bladder: introducing four contributions.

Neurogenic bladder dysfunction in children is frequently seen in patients with meningomyelocele (MMC). The disorder carries a high risk for all kinds of complications, with renal damage being the most important. More than 95% of MMC patients have a neurogenic bladder, the paramount manifestation of which is a disturbed coordination between detrusor and sphincter muscles.

Renal outcome of children with one functioning kidney from birth. A study of 99 patients and a review of the literature.

In patients with a single functioning kidney, renal function was assessed at regular intervals over a period of 10 years. Serum creatinine, glomerular filtration rate (GFR), blood pressure, and urinary protein-creatinine ratio were assessed at the age of 2, 5 and 10 years. Between January 1980 and December 2005, 99 such patients were diagnosed in the first year of life.

Schimke immunoosseous dysplasia: suggestions of genetic diversity.

Schimke immunoosseous dysplasia (SIOD), which is characterized by prominent spondyloepiphyseal dysplasia, T-cell deficiency, and focal segmental glomerulosclerosis, is a panethnic autosomal recessive multisystem disorder with variable expressivity. Biallelic mutations in switch/sucrose nonfermenting (swi/snf) related, matrix-associated, actin-dependent regulator of chromatin, subfamily a-like 1 (SMARCAL1) are the only identified cause of SIOD. However, among 72 patients from different families, we identified only 38 patients with biallelic mutations in the coding exons and splice junctions of the SMARCAL1 gene.

A classification of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and related disorders.

The diagnostic terms hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are based on historical and overlapping clinical descriptions. Advances in understanding some of the causes of the syndrome now permit many patients to be classified according to etiology. The increased precision of a diagnosis based on causation is important for considering logical approaches to treatment and prognosis.

Threading through the mizmaze of Bartter syndrome.

The story, described here in detail, started in 1962 with the publication of a seminal paper by Frederic Bartter et al. in the December issue of the American Journal of Medicine. The authors reported two pediatric patients with hitherto undescribed features, namely growth and developmental delay associated with hypokalemic alkalosis and normal blood pressure despite high aldosterone production.

Epidemiology, clinical presentation, and pathophysiology of atypical and recurrent hemolytic uremic syndrome.

Hemolytic uremic syndrome (HUS) includes a heterogeneous group of hemolytic disorders. Among the identified causes of HUS are infections, particularly infections with Shiga toxin-producing ESCHERICHIA COLI (STEC), complement disorders, and disorders interfering with the degradation of von Willebrand factor (VWF). Other causes for atypical HUS include the cobalamin metabolism; pregnancy/hemolysis, elevated liver enzymes, and low platelets syndrome (HELLP); drugs; and other disorders (e.

The best game is the waiting game.

Chronic dialysis and renal transplantation have been developed over the last three decades of the 20th century. These two forms of renal replacement therapy have revolutionized the fate of children in established renal failure. Yet, chronic dialysis is a serious burden to both the patient and the family and the long-term results of renal transplantation are far from excellent.

Renoprotection by ACE inhibitors after severe hemolytic uremic syndrome.

Five patients with severe hemolytic uremic syndrome (HUS) were followed for 10-18 years. Because of proteinuria, arterial hypertension, and reduced glomerular filtration rates, they received either captopril (n=2) or enalapril (n=3), or both (n=1) for 8-15 years. Blood pressure was normalized and proteinuria reduced in all; glomerular filtration improved in three patients and fell moderately in two.

Enalapril in children with Alport syndrome.

Ten pediatric patients with Alport syndrome received enalapril for 5 years. There were nine boys. Eight patients have the X-linked form of the disease and two the autosomal recessive form.

Pseudo-Bartter syndrome in a neonate on prostaglandin infusion.

Unlabelled: We describe a case of iatrogenic pseudo-Bartter syndrome caused by administration of prostaglandin E1 (PGE1 alprostadil). Although the use of i.v.

Renal biopsy 2-9 years after Henoch Schönlein purpura.

Twelve children and adolescents with classical Henoch-Schönlein purpura (HSP) underwent renal biopsy 2-9 years later. The clinical course was favorable in 10 of the patients who received only supportive treatment. Two patients with a prolonged course, characterized by marked hematuria and proteinuria, were given steroids and azathioprine first and mycophenolate mofetil later.

A girl with rickets and nephrocalcinosis.

A 5-year-old girl presented with short stature. She was found to have rickets due to renal phosphate wasting and nephrocalcinosis. Serum parathyroid hormone was suppressed, 25-OH vitamin D was within the normal range, and 1,25-(OH)(2 )vitamin D was elevated.