First application of behavoir recognition through the recording of ADL by radio modules in a home.

In this contribution the behavior of an elderly couple, recorded by a radio module system in their own home is analyzed. There is an increasing interest in giving elderly people the possibility to live at their own homes as long as possible. Since diseases like dementia are diagnosed through the change of behavior, especially the activities of daily living (ADL), there is a growing need of an objective instrument for measuring behavioral changes.

Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.

Neutrophil transmigration through venular walls that are composed of endothelial cells (ECs), pericytes, and the venular basement membrane is a key component of innate immunity. Through direct analysis of leukocyte-pericyte interactions in inflamed tissues using confocal intravital microscopy, we show how pericytes facilitate transmigration in vivo. After EC migration, neutrophils crawl along pericyte processes to gaps between adjacent pericytes in an ICAM-1-, Mac-1-, and LFA-1-dependent manner.