Release of Bisphenol A and Other Volatile Chemicals from New Epoxy Drinking Water Pipe Liners: The Role of Manufacturing Conditions.

Cured-in-place-pipe (CIPP) technology has begun to be adopted for drinking water pipe repairs, and limited information exists about its drinking water quality impacts. CIPP involves the manufacture of a new plastic pipe inside a buried damaged pipe. In this study, the chemical composition of the raw materials and CIPP water quality impacts were examined.

The development of the Agricultural Producer Barriers to Care Scale (APBCS).

Purpose: The purpose of this study was to identify and test the factor structure of the Agricultural Producer Barriers to Care Scale (APBCS), which assesses barriers to engaging with health care in rural US farmers.

Methods: Respondents (n = 1045) completed an online survey that was distributed digitally and in-person by researchers and community partners at farming events and via farm-related social media. Exploratory and Confirmatory Factor Analysis were used to assess the underlying factor structure of the APBCS, and McDonald's omega coefficients were calculated to test the reliability of each factor and the instrument as a whole.

Epigenetic biomarker for preeclampsia-associated preterm birth and potential preventative medicine.

Preterm birth (PTB) has dramatically increased within the population (i.e. >10%) and preeclampsia is a significant sub-category of PTB.

Root traits of soybeans exposed to polyethylene films, polypropylene fragments, and biosolids.

Biosolid use imports microplastics into the rhizosphere where they may interfere with root-soil-microbial interactions and cause morphological adaptations in crop root systems. Few studies have examined the response of crop roots to microplastics at documented soil concentrations, and many studies collect root traits using destructive techniques. Hence, there is little information on when and how microplastics effect the physical structure of root systems.

Referral pathway and competency profiles of primary care physiotherapists and kinesiologists for physical activity interventions for diabetes: a modified Delphi study.

Background: High quality diabetes care is an essential service in primary care settings since the prevalence and associated complications of diabetes is increasing. Physical activity is effective for the prevention and management of diabetes yet is underutilized in diabetes care. Exercise professionals have specialized skills to deliver physical activity interventions, but effective interprofessional collaboration for diabetes care requires role clarity.

Systems analysis of miR-199a/b-5p and multiple miR-199a/b-5p targets during chondrogenesis.

Changes in chondrocyte gene expression can contribute to the development of osteoarthritis (OA), and so recognition of the regulative processes during chondrogenesis can lead to a better understanding of OA. microRNAs (miRNAs) are key regulators of gene expression in chondrocytes/OA, and we have used a combined experimental, bioinformatic, and systems biology approach to explore the multiple miRNA-mRNA interactions that regulate chondrogenesis. A longitudinal chondrogenesis bioinformatic analysis identified paralogues miR-199a-5p and miR-199b-5p as pro-chondrogenic regulators.

"They Can't Possibly Understand What I'm Going Through": Female Farmers' Perspectives on Barriers to Care in Georgia.

The purpose of this study was to explore female farmers' perspectives on barriers to engaging with resources for physical and mental healthcare faced by agriculture producers in the state of Georgia. In-depth interviews were conducted with female farm owners and managers ( = 16) across the state. Interviews were recorded and transcribed, and researchers coded interviews separately before thematic analysis was used to identify common themes.

Survivor to thriver: identifying and overcoming the psychological effects of a stoma.

Stoma-forming surgery can have extensive, negative impacts on a patient's psychological wellbeing. Although this has been known for several decades, little progress has been made in addressing the issue. Several areas of concern have been repeatedly identified in the literature: loss of control; reduced self-esteem; psychosexual issues; and the impact of enhanced recovery on psychological outcomes.

Stroke studies in large animals: Prospects of mitochondrial transplantation and enhancing efficiency using hydrogels and nanoparticle-assisted delivery.

One of the most frequent reasons for mortality and disability today is acute ischemic stroke, which occurs by an abrupt disruption of cerebral circulation. The intricate damage mechanism involves several factors, such as inflammatory response, disturbance of ion balance, loss of energy production, excessive reactive oxygen species and glutamate release, and finally, neuronal death. Stroke research is now carried out using several experimental models and potential therapeutics.

NeuroRoots, a bio-inspired, seamless brain machine interface for long-term recording in delicate brain regions.

Scalable electronic brain implants with long-term stability and low biological perturbation are crucial technologies for high-quality brain-machine interfaces that can seamlessly access delicate and hard-to-reach regions of the brain. Here, we created "NeuroRoots," a biomimetic multi-channel implant with similar dimensions (7 m wide and 1.5 m thick), mechanical compliance, and spatial distribution as axons in the brain.

Origami-inspired soft fluidic actuation for minimally invasive large-area electrocorticography.

Electrocorticography is an established neural interfacing technique wherein an array of electrodes enables large-area recording from the cortical surface. Electrocorticography is commonly used for seizure mapping however the implantation of large-area electrocorticography arrays is a highly invasive procedure, requiring a craniotomy larger than the implant area to place the device. In this work, flexible thin-film electrode arrays are combined with concepts from soft robotics, to realize a large-area electrocorticography device that can change shape via integrated fluidic actuators.

Examining the Relationship Between Stress, Barriers to Healthcare, and Alcohol Use in the US Agricultural Community.

Objective: Farming is a high-risk, physically challenging occupation. Considering farmers report high stress and barriers to seeking healthcare, it is important to understand factors influencing alcohol use to tailor interventions and healthcare resources for alcohol use in rural areas.

Methods: An online survey was distributed to the agricultural community in the United States ( = 1045).

The Intersection of Gender and Occupational Roles in Agriculture: Stress, Resilience, and Alcohol Behaviors of US Farmers.

Objectives: The purposes of this study were to explore behavioral and mental health outcomes among a sample of farmers living in the United States and to compare differences between male and female farmers.

Methods: An online cross-sectional survey was distributed within the farming community by researchers, farming consultants, and community partners. χ 2 and analysis or variance analyses were used to explore relationships between variables of interest.

Erratum: Publisher's Note: "Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design" [APL Bioeng. , 046109 (2023)].

[This corrects the article DOI: 10.1063/5.0163264.

A rare encounter: Comprehensive case review of myxoid meningiomas with a representative case.

Meningiomas are the most diagnosed primary central nervous system tumor. Currently, 15 different subtypes of meningioma exist with various characteristics. One extremely rare subtype is myxoid meningioma, which is a World Health Organization grade 1 benign meningioma.

Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design.

Spinal cord injury (SCI) arises from damage to the spinal cord, often caused by trauma or disease. The resulting sensorimotor dysfunction is variable and dependent on the extent of the injury. Despite years of research, curative options for SCI remain limited.

Soft and Flexible Bioelectronic Micro-Systems for Electronically Controlled Drug Delivery.

The concept of targeted and controlled drug delivery, which directs treatment to precise anatomical sites, offers benefits such as fewer side effects, reduced toxicity, optimized dosages, and quicker responses. However, challenges remain to engineer dependable systems and materials that can modulate host tissue interactions and overcome biological barriers. To stay aligned with advancements in healthcare and precision medicine, novel approaches and materials are imperative to improve effectiveness, biocompatibility, and tissue compliance.

Four buildings and a flush: Lessons from degraded water quality and recommendations on building water management.

A reduction in building occupancy can lead to stagnant water in plumbing, and the potential consequences for water quality have gained increasing attention. To investigate this, a study was conducted during the COVID-19 pandemic, focusing on water quality in four institutional buildings. Two of these buildings were old (>58 years) and large (>19,000 m), while the other two were new (>13 years) and small (<11,000 m).

Cancer, now what? A cross-sectional study examining physical symptoms, subjective well-being, and psychological flexibility.

The impact of cancer extends beyond treatment and evaluating the adverse psychological effects in survivors is important. We examined: (1) the relationship between diagnosis, relapse, and subjective well-being using a short and a holistic measure of well-being, including comparisons between our sample and established norms; (2) if reported physical symptoms were related to components of subjective well-being; and (3) if increased psychological flexibility predicted overall subjective well-being. In total, 316 survivors completed online questionnaires to assess cancer, physical health (Edmonton Symptom Assessment Scale-R; ESAS-R), subjective well-being (Comprehensive Inventory of Thriving; CIT; Satisfaction with Life Scale; SWLS) and psychological flexibility (Comprehensive Assessment of Acceptance and Commitment Therapy).

Factors impacting neurosurgery residents' operative case volume: a nationwide survey.

Objective: Neurological surgery residency remains one of the most competitive and longest specialties in terms of training in medicine. The Accreditation Council for Graduate Medical Education uses residents' case volume throughout residency as one of its measures for the quality of surgical training. The objective was to study the variability of residency case volume among US training programs and to analyze the factors that potentially influence that case volume.

Having Outpatient Major Elective (HOME) Robotic Colon Resection Protocol: A Safe Approach to Ambulatory Colon Resection.

Background: Within the past decade, colorectal surgery length of stay (LOS) has decreased from an average of 5-6 days to 2-3 days. However, elective colon resections have yet to become a common procedure with the potential for same-day discharge. During the COVID pandemic, hospital capacity was exceptionally strained and colon resections were delayed due to the lack of inpatient beds available.

Understanding the Consumption of Antimicrobial Resistance-Related Content on Social Media: Twitter Analysis.

Background: Antimicrobial resistance (AMR) is one of the most pressing concerns in our society. Today, social media can function as an important channel to disseminate information about AMR. The way in which this information is engaged with depends on a number of factors, including the target audience and the content of the social media post.

Residential Water Softeners Release Carbon, Consume Chlorine, and Require Remediation after Hydrocarbon Contamination.

Water quality impacts of new ion exchange point-of-entry residential softeners and their ability to be decontaminated following hydrocarbon exposure were investigated. During startup, significant amounts of total sulfur (445 ± 815 mg/L) and total organic carbon (937 ± 119 mg/L) were released into the drinking water that flowed through the softeners. Particulate organic carbon was released until the third regeneration cycle, and resin may also have been released.

Furanone loaded aerogels are effective antibiofilm therapeutics in a model of chronic wound infection.

Almost 80% of chronic wounds have a bacterial biofilm present. These wound biofilms are caused by a range of organisms and are often polymicrobial. is one of the most common causative organisms in wound infections and readily forms biofilms in wounds.