Publications by authors named "Priyanshu Nain"
The Digital Revolution in Medicine: Applications in Cardio-Oncology.
Curr Treat Options Cardiovasc Med
December 2025
Purpose Of Review: A critical evaluation of contemporary literature regarding the role of big data, artificial intelligence, and digital technologies in precision cardio-oncology care and survivorship, emphasizing innovative and groundbreaking endeavors.
Recent Findings: Artificial intelligence (AI) algorithm models can automate the risk assessment process and augment current subjective clinical decision tools. AI, particularly machine learning (ML), can identify medically significant patterns in large data sets.
This review goes beyond traditional approaches in cardio-oncology, highlighting often-neglected factors impacting patient care. Social determinants, environment, health care access, and gut microbiome significantly influence patient outcomes. Powerful tools like multi-omics and wearable technologies offer deeper insights into real-world experiences.
View Article and Find Full Text PDFPurpose: External beam radiation therapy (EBRT) is a critical component of breast cancer (BC) therapy. Given the improvement in technology in the contemporary era, we hypothesized that there is no difference in the development of or worsening of existing coronary artery disease (CAD) in patients with BC receiving left versus right-sided radiation.
Methods And Materials: For the meta-analysis portion of our study, we searched PubMed, Web of Science, and Scopus and included studies from January 1999 to September 2022.
Background: Cardiovascular disease (CVD) and cancer frequently co-occur due to shared risk factors such as obesity, which is linked to CVD and 14 cancer types. This study explores whether CVD pathophysiologies, combined with obesity, increase cancer risk, impacting clinical management.
Methods And Results: Data from the ARIC (Atherosclerosis Risk in Communities) study, spanning 28 years, were analyzed.
Article Synopsis
- - Cancer survivors have a significantly higher risk of cardiovascular disease (CVD) and death from CVD, especially those under 65 years old, who face a 41% increased risk.
- - Allostatic load (AL), which measures the cumulative effects of chronic stress, plays a role in this increased risk, mediating between cancer survivorship and CVD mortality by varying percentages depending on age and race.
- - The study highlights disparities in CVD death risk among different racial groups, notably that Black cancer survivors under 65 years old have an 84% increased risk, possibly influenced by social determinants of health.
The role of social determinants of health (SDOH) in controlling hypertension (HTN) in cancer patients is unknown. We hypothesize that high SDOH scores correlate with uncontrolled HTN in hypertensive cancer patients. In our prospective study, patients completed the Protocol for Responding to & Assessing Patients' Assets, Risks & Experiences questionnaire.
View Article and Find Full Text PDFBackground: Cardiovascular disease and cancer share a common risk factor: chronic stress/allostatic load (AL). A 1-point increase in AL is linked to up to a 30% higher risk of major cardiac events (MACE) in patients with prostate cancer. However, AL's role in MACE in breast cancer, lung cancer, or colorectal cancer remains unknown.
View Article and Find Full Text PDFPregnancy-associated breast cancer is challenging to treat. Treatment with chemotherapeutic agents such as anthracyclines poses a risk of cardiotoxicity, despite being considered safe after the second trimester of pregnancy. Management requires multidisciplinary comanagement with cardio-obstetrics, cardiology-oncology, maternal-fetal medicine, and oncology.
View Article and Find Full Text PDFArticle Synopsis
- * Factors like genetics, environment, diet, and lifestyle contribute to conditions like obesity and diabetes, but emerging research highlights the gut microbiome's significant influence on metabolic syndrome and associated health risks.
- * Current studies are exploring treatments, such as prebiotics, probiotics, synbiotics, and postbiotics, to enhance beneficial gut bacteria and alleviate conditions related to metabolic syndrome by lessening inflammation and improving insulin sensitivity.
Background: Despite intravenous thrombolysis (IVT) being used for the treatment of acute ischemic stroke (AIS) for over two decades, its accessibility remains limited in various regions of the world. The Asian region, which experiences the highest age-standardized incidence of AIS, currently lacks comprehensive data on the utilization of IVT.
Aims: This study aimed to provide precise estimates of IVT usage for AIS in Asian countries.
Background: The recent outbreak of Human Monkeypox (MPXV) in nonendemic regions of the world is of great concern.
Objective: We aimed to systematically analyze the current epidemiology, clinical presentation, and outcomes of the Monkeypox virus.
Method: Systematic literature was conducted in PubMed, Embase, Google Scholar, and Scopus using predefined MESH terms by using "AND" and "OR.
Article Synopsis
- * Key features of gut dysbiosis related to type 2 diabetes include an altered ratio of Firmicutes to Bacteroidetes and a decrease in Akkermansia muciniphila, which can affect metabolic processes and contribute to disease complications.
- * Emerging research indicates a bidirectional relationship between gut microbiota and anti-diabetic medications, suggesting that medications can change gut microbiota composition, which in turn may influence medication effectiveness.