Introduction: The dearth of population-based data on polysubstance use, especially in young emerging adults, presents a critical gap in understanding public health challenges, particularly in rural India, where tobacco and oral cancer are prevalent. This study addresses this gap by investigating the prevalence and patterns of substance use, with a focus on young emerging adults (18-29 years) within a high-risk cohort for oral cancer in Varanasi, India.
Methods: The study involved a cross-sectional analysis of baseline data from 10,101 participants within a high-risk cohort in rural settings of the Varanasi district between December 2020-June 2023.
As space travel evolves from brief missions to longer expeditions, and with the rise of space tourism, there is increasing interest in understanding how space travel affects human reproductive physiology and the feasibility of procreation in space. Space travel presents various potential hazards to reproductive health such as exposure to ionizing radiation, exposure to changes in gravity, psychological stress, and disruptions to the endocrine and urogenital systems, as well as the circadian rhythm. This article explores how cosmic radiation and microgravity impact both female and male gametogenesis, embryogenesis, and reproductive physiology.
View Article and Find Full Text PDFDiamond-Like Carbon (DLC), a thin-film material, is emerging as a promising alternative for durable surfaces due to its eco-friendly application process. This study evaluated the use of thin-film DLC on the wafer surface of gravure cylinders for roll-to-roll printing of fine-line electrodes and microtext patterns, specifically for applications in flexible electronics and graphics security. Results suggested that using thin film DLC on the wafer surface allows reliable reproduction of isometric grids and line structures with widths of 15, 20, and 30 µm, as well as solid electrodes.
View Article and Find Full Text PDFJ Maxillofac Oral Surg
December 2024
Oral and maxillofacial surgery has seen various advancements throughout years. From dental implants to 3D printing, every advancement this field has witnessed has taken it one step ahead into the future. Reconstructive surgeries in oral and maxillofacial surgery have evolved drastically over the years.
View Article and Find Full Text PDFRegulated protein degradation plays a crucial role in maintaining proteostasis along with protein refolding and compartmentalisation which collectively control biological functions. The N-end rule pathway is a major ubiquitin-dependent protein degradation system. The short-lived protein substrates containing destabilizing amino acid residues (N-degrons) are recognized by E3 ubiquitin ligases containing UBR box domains (N-recognin) for degradation.
View Article and Find Full Text PDFThe escalating utilization of wireless electronic devices, notably cellular phones, has led to a substantial augmentation in the levels of electromagnetic field radiation (EMF-r) within the environment. Consequently, an imperative arises to investigate the impact of these radiations on biological systems, specifically on plants. In this study, we examined the genotoxic and cytotoxic effects of 2100 MHz and 2300 MHz EMF-r on the Trigonella foenum-graecum L.
View Article and Find Full Text PDFMonarda citriodora Cerv. ex Lag. is a rich source of industrially important compounds like γ-terpinene, carvacrol, thymol and thymoquinone.
View Article and Find Full Text PDFJ Family Med Prim Care
September 2024
Introduction: Hypothyroidism is among the most prevalent endocrine disorders worldwide. Its risk increases with menopause. The prevalence of hypothyroidism among menopausal women in India is unknown, as conclusive data are scarce.
View Article and Find Full Text PDFBackground: India bears the highest global burden of oral cancer, despite having an operational tobacco cessation framework. Occupational groups like solid waste management personnel face significant health challenges due to prevalent tobacco use, leading to oral potentially malignant lesions and oral cancer. Enhanced tobacco control strategies are essential for these groups.
View Article and Find Full Text PDFThe purpose of this study was to determine the relationship between triptans (sumatriptan, rizatriptan, and zolmitriptan) and cardiovascular (CV) adverse events with data from the FDA Adverse Event Reporting System (FAERS). FAERS database was used to collect data on triptans from 1997 to 2023. Disproportionality methods were utilized to quantify triptan-associated CV events and to identify the potential risk.
View Article and Find Full Text PDFMedical certification of the cause of death provides epidemiological information for developing cause-specific mortality and disease trends, guiding the monitoring of health programmes and allocating health resources. Therefore, providing correct information on the cause of death is essential. This study describes the errors in medical certification of the cause of death in India.
View Article and Find Full Text PDFWeakly fluorescent AuAg nanoclusters were obtained from glutathione, chloroauric acid, and silver nitrate aqueous solution under a modified hydrothermal method. Such glutathione-capped synergistically evolved clusters were obtained for the first time by employing our experimental conditions. Such weak fluorescence was made significantly brighter by employing Na and a Na sensor was obtained with a linear detection range of 10-5 × 10 M, while the limit of detection was 1.
View Article and Find Full Text PDFThe strong fluorescence of green tea was quenched with Fe because of ligand-to-metal charge transfer and subsequent formation of magnetite (FeO) nanoparticles (heavy metal effect). Ag restored the lost fluorescence by confining iron particles (capped with Cl) with the formation of AgCl. Thus, toxic Ag was sensed in the aqueous system with a linear detection range of 10 M to 10 M and a detection limit of 4.
View Article and Find Full Text PDFInt J Biol Macromol
November 2024
Exopolysaccharides (EPSs) from lactic acid bacteria (LAB) have multifunctional capabilities owing to their diverse structural conformations, monosaccharide compositions, functional groups, and molecular weights. A review paper on EPS production and antioxidant potential of different LAB genera has not been thoroughly reviewed. Therefore, the current review provides comprehensive information on the biosynthesis of EPSs, including the isolation source, type, characterization techniques, and application, with a primary focus on their antioxidant potential.
View Article and Find Full Text PDFObjective: To assess how well steroidal nasal sprays and oral steroids work for treating CRS.
Methods: Two hundred patients with CRS were included in a randomized controlled experiment. The patients were split into two groups: Group B received steroidal nasal sprays (fluticasone propionate 110 mcg/day in each nostril for 12 weeks) and Group A received oral steroids (prednisolone 30 mg/day for 14 days, followed by tapering over 7 days).
Background: Patient anxiety is known to influence various aspects of dental procedures, including endodontic treatments. However, the extent of its impact on the efficacy of such procedures remains uncertain. Understanding this influence is crucial for improving patient outcomes and optimizing treatment protocols.
View Article and Find Full Text PDFAsia Pac J Clin Oncol
December 2024
Breast cancer (BC) remains a global health challenge, devastatingly impacting women's lives. Low-and-middle-income countries (LMIC), such as India, experience a concerning upward trend in BC incidence, necessitating the implementation of cost-effective screening methods. While mammography, ultrasonography, and magnetic resonance imaging are preferred screening modalities in resource-rich settings, limited resources in LMICs make clinical breast examination (CBE) the method of choice.
View Article and Find Full Text PDFAmong the group 11 transition metal elements, Cu and Ag are widely studied due to their cost effectiveness and easy availability. However, the synergism between copper and silver is also very promising, exhibiting intriguing structures, properties, and applications. Nanoclusters, which are missing links between atoms and nanoparticles, are highly fluorescent due to their discrete energy levels.
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