Comparative Evaluation of Pain Perception with Conventional and Septoject XL Needle in 6-8-year-old Children: A Randomized Controlled Trial.

Aims And Background: To evaluate and compare pain perception with Septoject XL and conventional needles in 6-8 years old children.

Materials And Methods: In this split-mouth randomized controlled trial, a single-blinded study, 24 children (6-8 years) were assigned at random to receive the local anesthetic (LA) injection for treatment needs either with Septoject XL or conventional needle for the first visit in one of the quadrants, while during the second visit in a different quadrant with the other one. Children's pain levels were assessed during each visit using an objective sound eye motor (SEM) scale and subjective Wong-Baker faces rating scale (FRS).

Primary oral tuberculosis - A case report.

Tuberculosis is a chronic granulomatous disease which affects the lungs in majority of the cases. Oral manifestations of tuberculosis (TB) are seen both in primary and secondary stages of the disease but are most commonly associated with secondary TB. Primary oral TB is a rare entity and thus may pose a diagnostic challenge.

Comparative evaluation of shear bond strength and nanoleakage of conventional and self-adhering flowable composites to primary teeth dentin.

Background: The latest advancement in adhesive dentistry is the development of self adhering flowable composite resin which incorporates the self-etch adhesion technology to eliminate the steps of etching, rinsing, priming and bonding. Few studies have addressed resin bonding to primary teeth.

Aim: The aim of this study was to compare the shear bond strength and nanoleakage of conventional and self adhering flowable composites to primary teeth dentin.

Use of a high caloric liquid meal as an alternative to a solid meal for gastric emptying scintigraphy.

Background: Gastric emptying scintigraphy (GES) using a solid meal is often recommended for the evaluation of gastroparesis. However, some patients cannot tolerate the standardized egg-white sandwich (EWS) solid meal and an alternative meal is needed.

Aim: The aim of this study was to compare GES, regional gastric emptying, and gastric contractility using a liquid nutrient meal (LNM; Ensure Plus(®)) to those using EWS.

Clinical response and side effects of metoclopramide: associations with clinical, demographic, and pharmacogenetic parameters.

Objectives: Metoclopramide is associated with variable efficacy and side effects when used in the treatment of gastroparesis.

Aim: To determine associations of clinical and pharmacogenetic parameters with response and side effects to metoclopramide in patients with upper gastrointestinal symptoms suggestive of gastroparesis.

Methods: Gastroparetic patients treated with metoclopramide were enrolled.

Gastric emptying scintigraphy: is four hours necessary?

Introduction: Recommendations for gastric emptying scintigraphy (GES) suggest imaging over 4 hours to better define gastroparesis.

Aims: To determine the value of defining delayed gastric emptying at time points earlier than 4 hours.

Methods: GES was performed with ingestion of a liquid egg white meal with imaging at 0, 0.

Gastric emptying of solids and liquids for evaluation for gastroparesis.

Background: Gastric emptying scintigraphy (GES) of solids is typically used to evaluate for gastroparesis.

Aims: The purpose of this study was to determine the value of simultaneously measuring gastric emptying of liquids and solids for assessing patients for delayed gastric emptying.

Methods: A total of 596 patients at our institution from September 2007 to January 2010 underwent GES with assessment of both solid and liquid gastric emptying.

Domperidone treatment for gastroparesis: demographic and pharmacogenetic characterization of clinical efficacy and side-effects.

Background: Domperidone is a useful alternative to metoclopramide for treatment of gastroparesis due to better tolerability. Effectiveness and side-effects from domperidone may be influenced by patient-related factors including polymorphisms in genes encoding drug-metabolizing enzymes, drug transporters, and domperidone targets.

Aims: The aim of this study was to determine if demographic and pharmacogenetic parameters of patients receiving domperidone are associated with response to treatment or side-effects.

Abdominal pain is a frequent symptom of gastroparesis.

Background & Aims: Although the most commonly recognized symptoms of gastroparesis (GP) are nausea and vomiting, patients also report abdominal pain. We aimed to define the prevalence, severity, and quality of abdominal pain in GP and to correlate abdominal pain with gastric emptying (GE) and quality of life.

Methods: Patients presumed to have GP underwent 4-hour GE scintigraphy and upper endoscopy examinations and completed the following: patient assessments of gastrointestinal symptoms (Patient Assessment of Upper Gastrointestinal Symptom Severity Index), abdominal pain questionnaires (Short-Form of the McGill Pain Questionnaire), and quality-of-life questionnaires.