Publications by authors named "Priyali Wijeratne"
Background: High levels of antimicrobial resistance (AMR) are propagating deaths due to neonatal and paediatric infections globally. This is of particular concern in Southeast Asia and the Pacific, where healthcare resources are constrained and access to newer agents to treat multidrug-resistant pathogens is limited.
Methods: To assess the coverage provided by commonly prescribed empiric antibiotic regimens for children in low- and middle-income countries in Southeast Asia and the Pacific, we built a weighted incidence syndromic combination antibiogram (WISCA), parameterised using data obtained from a systematic review of published literature incorporating WHO-defined SEARO and WPRO regions in Ovid MEDLINE, EMBASE, Global Health and PubMed.
Clinical and Epidemiologic Profile of Invasive Pneumococcal Disease in Australian Children Following the Relaxation of Nonpharmaceutical Interventions Against SARS-COV-2.
Pediatr Infect Dis J
September 2023
Article Synopsis
- A global increase in invasive pneumococcal disease (IPD) among children has been observed, particularly in Australia after COVID-19 restrictions were eased.
- The analysis highlights severe health impacts from IPD, even in vaccinated children without prior health issues.
- Notably, nearly 50% of IPD cases were caused by serotypes not included in the 13-valent pneumococcal conjugate vaccine.