Absence of histologic retinal toxicity of intravitreal nanogold in a rabbit model.

Purpose: To evaluate the retinal toxicity of intravitreal nanogold, a novel antiangiogenic and long-term delivery agent.

Methods: One eye of each of 16 Dutch-belted rabbits was injected with intravitreal nanogold; the other eye served as a control. Eight rabbits received a dose of 67 micromol/0.