Publications by authors named "Priya Katwala"
Article Synopsis
- The study explores the link between periodontitis and the development of glucose intolerance (GI) and insulin resistance (IR), using a model involving liver Toll-like receptor 4 (TLR4) mechanisms.
- Chimeric mice with TLR4 were created to analyze the effects of chronic periodontitis induced by LPS, revealing significant bone loss and GI/IR in TLR4 positive chimeras.
- Despite differences in glucose tolerance, inflammatory cytokines such as IL1β, IL6, and TNFα showed no significant variation, suggesting that other factors may drive the GI/IR response connected to periodontitis.
