Publications by authors named "Priya F Gearin"
Acta Psychiatr Scand
May 2022
Article Synopsis
- Clozapine is underused due to clinicians' lack of knowledge and concerns about its adverse drug effects (ADEs), leading to reluctance in treatment.
- This systematic review analyzed 305 reports, ultimately summarizing 152 relevant studies on clozapine ADEs, revealing that most occur within the first 6 months after starting the medication.
- The review found that while many ADEs subside with dose adjustments, serious conditions like myocarditis and agranulocytosis should not be re-challenged, and high plasma levels of clozapine can increase the likelihood of certain ADEs.
