Laboratory investigations for any suspected case of solitary plasmacytoma of bone include routine biochemical and hematological investigations along with β2-microglobulin, electrophoresis of serum protein and/or 24-hour urine protein, serum protein immunofixation (IFE), and nephelometric quantification of total immunoglobulin isotype and serum free light chain levels. Bone marrow aspirate and trephine biopsy are mandatory to confirm the absence of clonal plasma cells (for solitary plasmacytoma) or the presence of less than 10% clonal cells (solitary plasmacytoma with minimal bone marrow involvement). Imaging studies such as X-ray, computed tomography (CT), magnetic resonance imaging, and positron emission tomography/CT should be used to complement laboratory tests in diagnosis, staging, and defining the local extent of the plasmacytoma.
View Article and Find Full Text PDFMonoclonal gammopathies (MGs) reflect conditions in which abnormal amounts of immunoglobulins are produced by a clone that developed from a single pro-B germ cell. They range from asymptomatic, benign disorders such as monoclonal gammopathy of undetermined significance to malignant plasma cell and lymphoid disorders, including multiple myeloma and Waldenstorm macroglobulinemia. The identification of the particular subtype of immunoglobulin molecule is done by serum immunofixation by use of specific antisera directed against different subtypes of immunoglobulin classes.
View Article and Find Full Text PDFMagnetic chitosan beads (MCSB), prepared from solution by using an external magnet, and the adsorption of Ni(II) ions from wastewater by MCSB and its cross-linked derivative with glutaraldehyde (GLU-MCSB) was investigated in an adsorption system. The GLU-MCSB sorbents are insoluble in aqueous acidic solution and improve adsorption capacity. The adsorption process was carried out by considering various parameters, viz.
View Article and Find Full Text PDFPolymethyl methacrylate grafted sodium alginate (SAG-g-PMMA) was synthesized by microwave assisted method. The grafting of the PMMA chains on the polysaccharide backbone was confirmed through intrinsic viscosity study, FTIR spectroscopy, elemental analysis (C, H, N, O and Na), SEM and TGA study. The intrinsic viscosity of sodium alginate appreciably improved on grafting of PMMA chains, thus resulting grafted product with potential application as superior viscosifier.
View Article and Find Full Text PDFPolyacrylamide chains (PAM) were grafted onto the backbone of gum ghatti by microwave assisted method. The grafting of the PAM chains on the polysaccharide backbone was confirmed through intrinsic viscosity study, FTIR spectroscopy, elemental analysis (C, H & N) and SEM morphology study. The intrinsic viscosity of gum ghatti appreciably improved on grafting of PAM chains, thus resulting grafted product with potential application as superior viscosifier.
View Article and Find Full Text PDFThis paper reports a novel microwave initiated method for synthesis of polyacrylamide grafted Psyllium (Psy-g-PAM). Psyllium was modified through grafting of polyacrylamide (PAM) chains on it using microwave radiations only, in absence of any other free radical initiator. The grafting was confirmed by intrinsic viscosity study and characterization techniques like FTIR spectroscopy, elemental analysis (C, H, N, O and S) and SEM morphology study.
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