Introduction: The incidence of arthritis is quite high and there is a need for the search of natural products to halt the progression of disease or provide symptomatic relief without significant adverse effects.
Aim: This study aimed at evaluating the anti-inflammatory and analgesic activities of topical in an animal model of chronic inflammation.
Materials And Methods: Albino rats of either sex were divided into five groups of six rats each (Group I - Control, Group II -Gel base, Group III - paste, Group IV - gel, Group V- Diclofenac gel).
Background: Careful consideration of the benefit to the mother and risk to the foetus, is required, while prescribing drugs during pregnancy.
Objectives: To assess the pattern of drug utilization during pregnancy and to explore the knowledge, attitude and awareness on drug use by the antenatal mother in a tertiary care hospital setup in western India.
Material And Methods: Observational, cross-sectional study involved holding interviews on 501 pregnant women, in OPD and IPD of Obstetrics-Gynaecology Department using a pilot-based questionnaire, was done.
Objectives: To study the effect of oral magnesium oxide supplementation alone and on the activity of standard anti-epileptic drugs in the animal models of maximal electroshock seizures (MES) and chemically (pentylenetetrazole [PTZ])-induced seizures.
Methods: Healthy male albino rats were given magnesium oxide (MgO) supplementation orally in various doses (500, 750 and 1000 mg/kg /day) for 4 weeks (day 1 to day 28). On day 0 and day 29, response to MES (180 mA for 0.