How Safe Are Common Analgesics for the Treatment of Acute Pain for Children? A Systematic Review.

. Fear of adverse events and occurrence of side effects are commonly cited by families and physicians as obstructive to appropriate use of pain medication in children. We examined evidence comparing the safety profiles of three groups of oral medications, acetaminophen, nonsteroidal anti-inflammatory drugs, and opioids, to manage acute nonsurgical pain in children (<18 years) treated in ambulatory settings.

Behavioral Programs for Type 2 Diabetes Mellitus: A Systematic Review and Network Meta-analysis.

Background: Behavioral programs may improve outcomes for individuals with type 2 diabetes mellitus, but there is a large diversity of behavioral interventions and uncertainty about how to optimize the effectiveness of these programs.

Purpose: To identify factors moderating the effectiveness of behavioral programs for adults with type 2 diabetes.

Data Sources: 6 databases (1993 to January 2015), conference proceedings (2011 to 2014), and reference lists.

Behavioral Programs for Type 1 Diabetes Mellitus: A Systematic Review and Meta-analysis.

Background: Whether behavioral approaches for self-management programs benefit individuals with type 1 diabetes mellitus is unclear.

Purpose: To determine the effects of behavioral programs for patients with type 1 diabetes on behavioral, clinical, and health outcomes and to investigate factors that might moderate effect.

Data Sources: 6 electronic databases (1993 to June 2015), trial registries and conference proceedings (2011 to 2014), and reference lists.