Publications by authors named "Priscille Olle"
Article Synopsis
- The study reviews the management and outcomes of necrotizing herpetic retinitis (NHR) to propose a first-line treatment algorithm, based on a retrospective analysis of 41 patients treated between 2012 and 2021.
- The majority of patients diagnosed with NHR were categorized into acute retinal necrosis (ARN), progressive outer retinal necrosis (PORN), and CMV retinitis, with a significant portion being immunocompromised.
- Findings indicate that complications were high, with 83% of eyes affected, and poor visual outcomes were linked to certain factors, emphasizing the need for prompt evaluation of immune status and timely antiviral treatment.
Article Synopsis
- Surgeries for children with idiopathic uveitis and juvenile arthritis are risky due to potential inflammatory issues post-operation, and there's no agreed approach to managing treatments during this time.
- A study was conducted in six French hospitals from 2006 to 2018 involving 76 surgeries on 37 children, examining the impact of continuing or stopping immunosuppressive therapies.
- Results indicated that stopping immunotherapy before surgery led to a 100% relapse rate within three months, while only 25% experienced relapse when therapies were maintained, suggesting it's safer to continue treatment.*
Article Synopsis
- * Results showed that 40 out of 57 patients achieved a complete response after chemotherapy, with no severe toxicity or treatment discontinuation due to side effects noted.
- * Although the treatment improved overall survival rates, a significant recurrence of the disease was observed, particularly in the eyes and brain, indicating a need for better strategies to manage local disease control and to monitor specific biomarkers like aqueous humor IL-10.
Main Objective: To prospectively assess the cost-consequence of a standardized diagnostic strategy as to compared to an open one for the etiological diagnosis of uveitis.
Design: This was a prospective, non-inferiority, multicentre, randomized controlled trial.
Methods: We included all consecutive patients with uveitis who had visited at least one of the Departments of Ophthalmology.
Objective: To assess the cytological diagnosis and follow-up of patients suffering from vitreoretinal lymphoma (VRL) diagnosed in our institution.
Methods And Results: From January 2010 to June 2017, we collected 15 patients with VRL. Twelve patients had diffuse large B-cell lymphoma (DLBCL); of these, 11 had primary central nervous system (CNS) DLBCL, one had ocular localisation of follicular lymphoma, one had extranodal NK/T-cell nasal type lymphoma and one had chronic lymphocytic leukaemia.
Contribution of diagnostic tests for the etiological assessment of uveitis, data from the ULISSE study (Uveitis: Clinical and medicoeconomic evaluation of a standardized strategy of the etiological diagnosis).
Autoimmun Rev
April 2018
Purpose: ULISSE is the only study that prospectively assessed the efficiency of a standardized strategy, compared to an open strategy for the etiologic diagnosis of uveitis. Our aim was to evaluate the diagnostic yield of the tests prescribed in the ULISSE study to clarify their relevance.
Methods: ULISSE is a non-inferiority, prospective, multicenter and cluster randomized study.
Purpose: To prospectively assess the efficiency of a standardized diagnostic approach, compared to an open strategy, for the etiologic diagnosis of uveitis.
Design: Noninferiority, prospective, multicenter, clustered randomized controlled trial.
Methods: Consecutive patients with uveitis, who visited 1 of the participating departments of ophthalmology, were included.
Aims: To improve the cytological diagnosis of retinal lymphoma on vitreous fluid using improved cell collection and systematic analyses.
Methods And Results: Since October 2010, we have developed and optimized in our department a method with which to perform the diagnosis of retinal lymphoma. The vitreous sample was collected in a tube containing RPMI-1640 medium, decomplemented fetal bovine serum, and gentamicin.