Publications by authors named "Priscilla Caputi"
Article Synopsis
- From August to November 2023, Italy reported 82 local cases of Dengue virus (DENV), with 10 cases specifically studied in Rome, showcasing a shift toward local transmission of the disease.
- The affected patients, mostly middle-aged and presenting classic dengue symptoms, were confirmed to have the virus through various laboratory tests including detection of DENV proteins and antibodies.
- The study emphasizes the importance of developing better surveillance and diagnosis strategies for DENV infections in non-endemic regions, to manage and understand the clinical progression of the disease.
Article Synopsis
- Bullous pemphigoid (BP) is a rare autoimmune skin disorder, becoming more frequent with associations noted with certain diabetes medications called gliptins.
- A study analyzed 30 idiopathic bullous pemphigoid (IBP) patients and 86 gliptin-associated BP (GABP) patients to explore genetic risk factors.
- The research found a significant link between the HLA-DQB1*03:01 allele and both IBP and GABP, suggesting genetic markers that could indicate susceptibility to BP, particularly in individuals who have taken gliptins.
Since August 2023, outbreaks of dengue virus (DENV) infection have occurred in Italy. We report 2 autochthonous case-patients and their extended follow-up. Despite persistent DENV detected in blood by PCR, results for antigenomic DENV RNA were negative after day 5, suggesting that a 5-day isolation period is adequate to avoid secondary cases.
View Article and Find Full Text PDFBackground: Remdesivir is a prodrug of the nucleoside analogue GS-441524 and is under evaluation for treatment of SARS-CoV-2-infected patients.
Objectives: To evaluate the pharmacokinetics of remdesivir and GS-441524 in plasma, bronchoalveolar aspirate (BAS) and CSF in two critically ill COVID-19 patients.
Methods: Remdesivir was administered at 200 mg loading dose on the first day followed by 12 days of 100 mg in two critically ill patients.