Gingival crevicular fluid biochemical markers in periodontal disease: a cross-sectional study.

Objective: To evaluate the levels of interleukin-1b (IL-1b) and alkaline phosphatase (ALP) in gingival crevicular fluid (GCF) and correlate these measurements with clinical characteristics of healthy patients and patients with gingivitis and periodontitis.

Method And Materials: Thirty-six individuals were subdivided into three groups of 12: control, gingivitis, and periodontitis groups. GCF samples were obtained from 2 sites for each patient.