Urticaria and Prodromal Symptoms Including Erythema Marginatum in Danish Patients with Hereditary Angioedema.

Erythema marginatum is a characteristic skin rash seen in patients with hereditary angioedema (HAE); however, it can be confused with urticaria, leading to delay in correct diagnosis. The aim of this study was to clarify how often erythema marginatum is misinterpreted as urticaria, potentially leading physicians to refrain from testing for HAE. Few studies have been published on urticaria and prodromal symptoms in HAE, thus the incidence of these parameters were also investigated.

Effect of l-glutamine on myenteric neuron and of the mucous of the ileum of diabetic rats.

The objective of this work was to investigate the effect of the L-glutamine supplementation to prevent - diabetes induced changes in myenteric neurons and also to verify the effect on the mucosa of the ileum of Wistar rats. The animals were divided in five groups (n = 5): untreated normoglycaemic (UN), normoglycaemic treated with L-glutamine (NG), untreated diabetics (UD), diabetics treated with L-glutamine, starting on the 4th (DG4) or 45th day following diabetes induction (DG45). The amino acid was added to the diet at 1%.

Neuroprotection and neurodegeneration in submucosal VIP-IR neurons in the jejunum of ascorbic acid supplemented aging Wistar rats.

The present work studied the effects of ascorbic acid supplementation (1 mg/ml in water daily) on submucosal vasoactive intestinal polypeptide-immunoreactive (VIP-IR) neurons in the jejunum of aging rats. Twenty-five male rats were divided into the following groups: Y90 (young, 90-day-old rats), A345 (aged, 345-day-old rats), A428 (aged, 428-day-old rats), AA345 (ascorbic acid-supplemented rats, 90-345-day old), and AA428 (ascorbic acid-supplemented rats, 90-428-day old). Whole mounts of the submucosal layer were subjected to immunohistochemistry for determination of VIP-IR.

Management of dens invaginatus type III with large periradicular lesion.

Aim: This study describes a clinical case of type III dens invaginatus with an extensive periradicular lesion treated successfully.

Background: Dens invaginatus is a maldevelopment of the dental germ which occurs as a result of the invagination of the enamel organ. These cases may present difficulties with respect to its diagnosis and treatment because of canal morphology.

Myenteric neurons and intestinal mucosa of diabetic rats after ascorbic acid supplementation.

Aim: To investigate the effect of ascorbic acid (AA) dietary supplementation on myenteric neurons and epithelial cell proliferation of the jejunum of adult rats with chronic diabetes mellitus.

Methods: Thirty rats at 90 d of age were divided into three groups: Non-diabetic, diabetic and diabetic treated with AA (DA) (1 g/L). After 120 d of treatment with AA the animals were killed.

Alterations of the number and the profile of myenteric neurons of Wistar rats promoted by age.

The objective of this study was to analyze the morpho quantitative behaviour of duodenum myenteric neurons of Wistar rats (Rattus norvegicus), aged 21, 60, 90, 210, 345 and 428 days, using wholemount preparations of the muscular tunica obtained by dissecting the intestinal tunica for neuronal revealing, through the Giemsa non-histochemical and Myosin-V immunohistochemical techniques. The neurons were quantified in 80 microscopic fields (14.832 mm(2)) for each animal and neuronal cell body morphometry was carried out on 100 neurons/rat.

Myenteric denervation differentially reduces enteroendocrine serotonin cell population in rats during postnatal development.

The enteric nervous and enteroendocrine systems regulate different processes in the small intestine. Ablation of myenteric plexus with benzalkonium chloride (BAC) stimulates epithelial cell proliferation, whereas endocrine serotonin cells may inhibit the process. To evaluate the connection between the systems and the influence of myenteric plexus on serotoninergic cells in rats during postnatal development, the ileal plexus was partially removed with BAC.

Effects of ascorbic acid on the vasoactive intestinal peptide synthesis in the ileum submucous plexus of normal rats.

Background: The aging process is a deteriorating process that attacks the gastrointestinal tract, causing changes in the number and size of neurons from the enteric nervous system. The activity of free radicals on enteric neurons is helped by the significant reduction of antioxidants.

Aim: Evaluate the effect of the ascorbic acid supplementation on the neurons that produce the vasoactive intestinal peptide (VIP) in the submucous plexus of the ileum of normal rats for a period of 120 days.

Effects of a hypoproteic diet on myosin-V immunostained myenteric neurons and the proximal colon wall of aging rats.

The objective of this work was to analyze the morphoquantitative behavior of neurons of the myenteric plexus, as well as the morphometry of elements of the proximal colon wall of Wistar rats (Rattus norvegicus) fed a normoproteic (22%) and a hypoproteic (8%) diet, and sacrificed at 360 days of age. To perform the neuronal evaluation, we used whole-mount preparations of the proximal colon immunostained with the antibody anti-myosin-V. The neurons were quantified in 80 microscopic fields (16.