Assessment of proadrenomedullin as diagnostic or prognostic biomarker of acute appendicitis in children with acute abdominal pain.

Background: Acute appendicitis (AA) is one of the most frequent surgical pathologies in pediatrics.

Objectives: To investigate the utility of proadrenomedullin (pro-ADM) for the diagnosis of AA.

Methods: Prospective, analytical, observational, and multicenter study conducted in 6 pediatric emergency departments.