Publications by authors named "Priscila Hiane"

Article Synopsis
  • This study assessed the effects of ethanolic and aqueous extracts from a plant's bark on mice fed a high-fat diet and analyzed the extracts' chemical composition.
  • The results indicated that while the aqueous extract had better antioxidant properties, neither extract significantly affected weight gain or fat accumulation, but they did decrease food intake.
  • Additionally, the extracts increased leptin levels, which might promote feelings of fullness, but negatively impacted other inflammatory and hormonal markers, showing no effective treatment for diet-related metabolic issues.
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Grape seeds are rich in bioactive substances, including polyphenols, terpenoids, and phytosterols. Linseed ( L.) boasts a high concentration of polyunsaturated fatty acids (PUFAs), lignans, phytoestrogens, and soluble fibers, all contributing to its therapeutic potential.

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  • Pantanal, a unique biome in Brazil, is rich in diverse plant and animal species, including native rice varieties Oryza latifolia and Oryza rufipogon, which are significant due to increased rice consumption worldwide, particularly in Asia and Africa.
  • The average rice consumption is about 160 g/day, but it poses health risks due to potential ingestion of harmful substances like toxic metals.
  • This study analyzed seven types of Brazilian rice for essential and toxic elements; findings indicated that chromium levels were highest in native species, and all varieties had risks associated with inorganic arsenic, highlighting the need for further research on contamination and its health implications.
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  • * An aqueous extract of the plant was prepared and tested in rats, revealing that while there were some symptoms indicative of toxicity, the overall lethality was low, with most animals surviving.
  • * The examination of organs post-mortem indicated some necrosis and other changes in dead rats, but overall, the extracted plant showed low toxicity effects on body mass and organ macroscopic evaluation.
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L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65-75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catechins (414 mg), epicatechins (130.

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People are constantly exposed to particulate matter and chemicals released during fires. However, there are still few studies on gas and particulate emissions related to exposure to burning firewood and charcoal during forest fires, making it difficult to understand the effects on the health of the population. The objective of this study was to quantify the metal(loid)s present in the smoke from wood and charcoal fires through the deposition of metals in beef topside and pork loin, considering the routes of skin exposure, inhalation, and ingestion, contributing to the understanding of metals in the increase of the risks of cancer and mortality associated with firefighting and children.

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  • Maternal dietary choices, particularly the intake of polyunsaturated fatty acids (PUFAs), and gut microbiota influence fetal brain development and may play a role in Autism Spectrum Disorder (ASD) risk.
  • Higher consumption of linoleic acid (LA, a n-6 PUFA) is linked to negative effects on gut health and increased inflammation, whereas α-linolenic acid (ALA, a n-3 PUFA) can promote gut health and reduce inflammation.
  • Observational studies suggest that a high intake of n-3 PUFAs, like fish, benefits infant neurodevelopment, indicating that proper maternal nutrition could help lower ASD risk, but more controlled research is needed to determine effective supplementation strategies. *
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The study of medicinal plants, such as the genus (Clusiaceae), in the treatment of non-communicable chronic diseases has aroused the interest of researchers. However, there are no studies in the literature that have investigated the effects of in experimental models of obesity for possible metabolic alterations. Swiss mice receiving a high-fat diet were supplemented with aqueous or ethanolic extract of at doses of 200 or 400 mg/kg/day.

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The consumption of regular vegetable oils has been linked to energy acquisition, nutritional benefits, health improvement, and the regulation of metabolic diseases. This study evaluated fatty acids composition, physicochemical, thermal, oxidative, and optical properties, and quantified trace elements in the sunflower oil extracted by a domestic cold-press machine. The oil presented linoleic (54.

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Background: Studies indicate that different parts of Linn have nutritional properties that mean it can be used as an adjuvant for the treatment of various pathologies.

Methods: The fatty acid composition of the oil extracted from the seeds of Linn was evaluated by gas chromatography, and an acute toxicity test was performed. For the experiment, Swiss mice were fed a balanced or high-fat diet and supplemented with saline, soybean oil, olive oil, or papaya seed oil.

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  • Buriti pulp oil contains beneficial bioactive substances and lipids that may help protect against cardiovascular and inflammatory diseases.
  • In a study with 108 Swiss mice over 90 days, various combinations of buriti oil and olive oil were tested, showing stability and effective metabolic interactions without affecting food intake or weight gain.
  • The strongest cardioprotective effect was seen in the group combining buriti oil and extra virgin olive oil, suggesting that this combination could be a valuable dietary supplement for people.
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  • - Antioxidants have gained attention from scientists for their potential to help prevent various degenerative diseases, but their effectiveness in the body needs further investigation.
  • - Current research faces challenges, including a lack of standardized methods for testing antioxidant activities, which leads to conflicting results in studies.
  • - This study seeks to address these challenges by reviewing common lab methods for assessing antioxidants, their actual biological impact, the importance of antioxidant enzymes, and how the bioavailability of these compounds is measured in both animal studies and human trials.
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The fruit and leaves of DC., locally known as , are rich in antioxidant glycosylated quercetin derivatives and phenolic compounds that have beneficial effects on diabetes mellitus, hypertension and general inflammation. We conducted a literature search to investigate the nutraceutical potentials of these phenolic compounds for treating obesity, diabetes mellitus and intestinal inflammatory disease.

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The aim of this article was to review experimental and clinical studies regarding the use of omega-3 fatty acids on the prevention and control of chronic inflammatory diseases with autoimmune background through the gut microbiota modulation. For this, natural omega-3 sources are presented emphasizing the importance of a healthy diet for the body's homeostasis and the enzymatic processes that these fatty acids go through once inside the body. The pathogenesis of ulcerative colitis and rheumatoid arthritis are revisited under the light of the gut microbiota dysbiosis approach and how those fatty acids are able to prevent and control these two pathological conditions that are responsible for the global chronic burden and functional disability and life-threatening comorbidities if not treated properly.

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Different fatty acid proportions produce potential inflammatory and metabolic changes in organisms. However, the evidence for how each fatty acid mediates the metabolic pathway, and its lipid stability remains controversial. To resolve this controversy, the present study investigated the metabolic effects of cold-pressed linseed (LG), coconut (CG), and baru (BG) oils in comparison to those of soybean oil (SG) in mice, in terms of their oil characterization and stability.

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Article Synopsis
  • - Obesity is linked to major global health issues, while diets high in fruits, vegetables, and fish can help decrease obesity and related metabolic diseases.
  • - The review focuses on the benefits of polyphenols and omega-3 fatty acids (ω-3 PUFAs), showing that foods rich in these compounds can lead to reduced obesity rates.
  • - The authors call for collaboration among research institutions and health ministries to create food education programs aimed at teaching healthy eating habits in schools and communities to combat obesity.
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Purpose: To develop a model of induction of type-2 diabetes (DM2) by combining low doses of streptozotocin (STZ) and a cafeteria diet.

Methods: Forty male Wistar rats (200 g) were allocated into four groups: control (non-diabetic, n = 10); STZ 30 mg/kg (diabetic, n = 10); STZ 35 mg/kg (diabetic,n = 10); and STZ 40 mg/kg (diabetic, n = 10). DM2 was induced with a single intraperitoneal injection of STZ after four weeks of cafeteria diet in the three diabetic groups.

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Functional clinical nutrition is an integrative science; it uses dietary strategies, functional foods and medicinal plants, as well as combinations thereof. Both functional foods and medicinal plants, whether associated or not, form nutraceuticals, which can bring benefits to health, in addition to being included in the prevention and treatment of diseases. Some functional food effects from L.

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  • Obesity is a chronic health issue linked to serious health problems and global mortality, prompting research on dietary solutions.
  • A study evaluated the effects of lyophilized pulp from a Brazilian palm when added to a high-fat diet in mice over 90 days, testing different concentrations (1%, 2%, 4%).
  • Results showed that 4% pulp improved HDL cholesterol levels and reduced fat deposits in mice compared to those on a high-fat diet alone, highlighting the health benefits of palm pulp’s fibers and monounsaturated fatty acids.
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  • This study investigates heavy metal and metalloid levels in fruit pulp from an area with high vehicle traffic and intensive farming to assess health risks for human consumption.
  • Ripe fruits were collected from three locations (roadside, bush, and farm-margin), and elements like K, Pb, Se, and others were quantified using advanced chemical techniques.
  • The findings showed that concentrations of harmful elements like arsenic (As) and lead (Pb) exceeded safety standards, with farm-margin samples having the highest levels, suggesting significant cancer risks with daily consumption.
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Carotenoids are vital antioxidants for plants and animals. They protect cells from oxidative events and act against the inflammatory process and carcinogenesis. Among the most abundant carotenoids in human and foods is β-carotene.

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During pregnancy, women undergo metabolic and physiological changes, and their needs are higher, to maintain growth and development of the fetus. If the nutritional status of the expectant mother is not satisfactory, some maternal and neonatal complications can occur. In the second and third trimester of pregnancy, there is a reserve of nutrients in the fetus that can be utilized after birth; thereby, children present an accelerated growth in the first years of life, which is a proven response to the available nutrition pattern.

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The aim of this study was to evaluate the therapeutic effects of two different doses (250 and 500 mg/kg) of fruit aqueous extract (AE) in high-fat/high-fructose-fed Swiss mice. The food intake, body weight, serum biochemical, oral glucose tolerance test (OGTT), and enzyme-linked immunosorbent assay (ELISA), as well as histological analyses of the liver, pancreatic, and epididymal adipose tissue, were used to determine the biochemical and histological parameters. The chemical profile of the extract was determined by ultra-fast liquid chromatography-diode array detector-tandem mass spectrometry (UFLC-DAD-MS), and quantitative real-time PCR (qRT-PCR) was used to evaluate the gene expressions involved in the lipid and glucose metabolism, such as peroxisome proliferative-activated receptors-γ (PPAR-γ), -α (PPAR-α), fatty acid synthase (FAS), glucose-6-phosphatase (G6P), sterol regulatory binding protein-1c (SREBP-1c), carbohydrate-responsive element-binding protein (ChREBP), and fetuin-A.

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The fruit of Cambess. is a source of oil with active compounds that are protective to the organism. In our work, we analyzed the physicochemical characteristics and evaluated the effects of supplementation with oil in an animal model.

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is a genus of Clusiaceae, distributed throughout tropical Asia, Africa, New Caledonia, Polynesia, and Brazil. plants contain a broad range of biologically active metabolites which, in the last few decades, have received considerable attention due to the chemical compositions of their extracts, with compounds which have been shown to have beneficial effects in several diseases. Our work had the objective of reviewing the benefits of five species (, , , , and ).

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