Multivitamins do not improve radiation therapy-related fatigue: results of a double-blind randomized crossover trial.

Background: Fatigue is a common symptom in cancer patients receiving radiation therapy.

Patients And Methods: We conducted a double-blind randomized crossover trial of multivitamins versus placebo in patients with breast cancer undergoing radiation therapy to evaluate fatigue and quality of life.

Results: : We randomized 40 patients to either placebo or Centrum Silver.