Publications by authors named "Pringsheim T"
Toxin for Tics: Practical Guidance for Clinicians from a Registry-Based Naturalistic Study.
Mov Disord Clin Pract
December 2024
Background: Botulinum toxin is a recommended treatment for tics. There is little practical guidance on the use of this treatment.
Objectives: Our aim is to describe our experience using botulinum toxin injections for tics in adults.
Background: Transcranial direct current stimulation (tDCS) over the supplementary motor area (SMA) has shown promise in Tourette syndrome (TS), but previous studies were limited in size and stimulation duration.
Objective: The aim was to explore the efficacy and safety of multiple sessions of cathodal tDCS over the bilateral SMA on tic severity in TS.
Methods: A double-blind, randomized, sham-controlled trial 1 mA cathodal tDCS over bilateral SMA was performed in participants with TS older than 16 years.
Evidence-based guidelines for anxiety, depression, obsessive-compulsive disorder and Tourette syndrome in children and youth: A rapid review.
J Can Acad Child Adolesc Psychiatry
November 2024
Article Synopsis
- The Canadian Institutes of Health Research is funding the development of national standards for mental health services for children and youth due to the rising demand for such interventions in Canada.
- A rapid review was conducted to gather evidence-based recommendations for assessing and treating conditions like anxiety, depression, OCD, and Tourette syndrome among children and youth.
- The review found consistent guidelines recommending psychological therapies as the first-line treatment, emphasizing the need for trained mental health professionals to ensure these services are effectively delivered.
Behavioural Therapy for tic disorders: a comprehensive review of the literature.
Expert Rev Neurother
December 2024
Article Synopsis
- Behavioral therapies, like comprehensive behavioral intervention for tics (CBIT), habit reversal therapy (HRT), and exposure and response prevention (ERP), are recommended as the first-line treatment for Tourette syndrome and tic disorders.
- Research shows that face-to-face CBIT is effective, and videoconferencing can deliver similar benefits; however, group treatments may not be as effective as individual therapy.
- There are promising findings for internet-based therapies, and ongoing efforts aim to enhance access to these behavioral treatments for those with tic disorders.
Article Synopsis
- A study conducted on Huntington's disease (HD) in Latin America found that previous global reviews have overlooked significant regional data, prompting a search across Spanish, Portuguese, and English databases to gather relevant studies.
- The research identified 24 studies from 12 of the 36 Latin American countries, revealing a pooled prevalence of HD at 0.64 per 100,000 people, with higher rates specifically in Mexico, Peru, and Brazil.
- The authors suggest that the actual prevalence of HD may be underestimated due to limited research, underdiagnosis, and insufficient access to molecular testing and specialists in the region, emphasizing the need for further studies to enhance understanding and access to care.
Premonitory Urge in Patients with Tics and Functional Tic-like Behaviors.
Mov Disord Clin Pract
March 2024
Article Synopsis
- * Researchers compared the premonitory urge for tics scale (PUTS) scores between 83 tic patients and 40 FTLB patients, finding no significant differences.
- * The results suggest that FTLB patients experience PU with similar frequency and intensity as those with tics, indicating PU is not effective in distinguishing between the two conditions.
Psychological Factors Associated with Functional Tic-like Behaviours during the COVID-19 Pandemic.
Res Child Adolesc Psychopathol
July 2024
Article Synopsis
- The study examines functional tic-like behaviors (FTLB), primarily affecting females, and notes a rise in cases during the COVID-19 pandemic, comparing them to individuals with Tourette Syndrome (TS) and neurotypical (NT) peers.
- Participants with FTLB displayed significantly higher rates of psychiatric disorders, including major depressive disorder and anxiety issues, and reported a further decline in mental health during the pandemic compared to TS and NT groups.
- FTLB participants also experienced more challenges like loneliness and trouble with basic needs, and a higher prevalence of identifying as gender minorities, though no gender differences were found within the FTLB group itself.
Background And Objectives: Lifestyle behaviors have been postulated to affect headache frequency in youth and are often the primary target of self-management recommendations. Our study aimed to assess the association between various lifestyle factors and frequent recurrent headaches in children and youth.
Methods: Children and adolescents aged 5-17 years were enrolled in a large cross-sectional Canadian population-based health survey, completed on January 31, 2019.
Article Synopsis
- A study was conducted to evaluate the effectiveness of specific criteria set by the European Society for the Study of Tourette Syndrome (ESSTS) for diagnosing functional tic-like behaviors (FTLBs) in children and adolescents with tic disorders.
- The analysis involved assessing the phenomenological characteristics of tic disorders using the Yale Global Tic Severity Scale on participants collected in Calgary, Canada, over specific years.
- Results showed that the ESSTS criteria demonstrated high specificity, particularly regarding age of onset and presence of complex tics, suggesting their usefulness in clinical diagnosis of FTLBs.
Article Synopsis
- * Researchers analyzed data from 236 youths, finding that FTLBs are more common in females and often involve behaviors like copropraxia, vocalizations, and self-injury.
- * The findings aim to assist healthcare professionals in diagnosing FTLBs by identifying specific associated movements and vocalizations.
Background And Purpose: Very little is known about the long-term prognosis of patients with functional tic-like behaviours (FTLBs). We sought to characterize the trajectory of symptom severity over a 12-month period.
Methods: Patients with FTLBs were included in our prospective longitudinal child and adult clinical tic disorder registries at the University of Calgary.
Article Synopsis
- Tics are involuntary and repetitive movements or sounds that differ from compulsive behaviors, and they have unique features such as a premonitory urge and ability to be suppressed.
- Tourette syndrome (TS), which is common in school-aged boys, is characterized by multiple motor and vocal tics over a year and is highly heritable, often accompanied by mental health issues like ADHD and OCD.
- Treatment for tics includes behavioral therapies and medication, with deep brain stimulation as an option for severe cases; most individuals experience a reduction in tic severity by adulthood.
Background: Adenylyl cyclase 5 (ADCY5)-related movement disorder (ADCY5-RMD) is a rare, childhood-onset disease resulting from pathogenic variants in the gene. The clinical features, diagnostic options, natural history, and treatments for this disease are poorly characterized and have never been established through a structured approach.
Objective: This scoping review attempts to summarize all available clinical literature on ADCY5-RMD.
Introduction: Eight members of the International Parkinson's Disease and Movement Disorders Society Tic and Tourette Syndrome Study Group formed a subcommittee to discuss further barriers to practice guideline implementation. Based on expert opinion and literature review, the consensus was that practice variations continue to be quite broad and that many barriers in different clinical settings might negatively influence the adoption of the American Academy of Neurology and the European Society for the Study of Tourette Syndrome published guidelines.
Objectives: 1) To identify how clinical practices diverge from the existing American Academy of Neurology and European Society for the Study of Tourette Syndrome guidelines, and 2) to identify categories of barriers leading to these clinical care gaps.
Background And Purpose: Developmental stuttering and Tourette syndrome (TS) are common neurodevelopmental disorders. Although disfluencies may co-occur in TS, their type and frequency do not always represent pure stuttering. Conversely, core symptoms of stuttering may be accompanied by physical concomitants (PCs) that can be confused for tics.
View Article and Find Full Text PDFBackground: Youth and parent engagement is a key component of clinical research. There are many ways to actively and meaningfully engage youth and parents as integral members of research teams, for example, through ad-hoc committees, advisory councils, or as co-leads on projects. When youth and parents are actively and meaningfully engaged in research projects, they share knowledge from their lived experiences to improve the quality and relevance of research.
View Article and Find Full Text PDFBackground: The first systematic description of tics in a large sample was in 1978.
Objectives: To assess the phenomenology of tics in youth and investigate how age and sex influence tic phenomenology.
Methods: Children and adolescents with primary tic disorders have been prospectively included in our Registry in Calgary, Canada, since 2017.
Article Synopsis
- The International Parkinson and Movement Disorders Society (MDS) formed a task force to develop guidelines for transitioning pediatric patients with movement disorders to adult healthcare systems.
- A formal consensus was established through a multi-round Delphi survey, informed by literature reviews and surveys of MDS members on transition practices, with input from 23 expert neurologists worldwide.
- The task force produced 15 consensus recommendations focusing on team structure, planning, care goals, and research needs, while highlighting challenges in implementation due to healthcare resource distribution and the need for further research on transitional care outcomes.