Road toward universal COVID-19 testing method - A review.

Patients infected with novel coronavirus exhibit a wide range of symptoms from common cold to pneumonia. Furthermore, several cases have been reported as asymptomatic across the globe. Since there are no conclusive clinical manifestations, clinicians have to rely more on laboratory diagnostic methods for confirmation of coronavirus disease.

Cytokine Analysis: A Fresh Perspective.

It is recognized that a balance of different cytokines (synergistic versus antagonistic cytokines) determines the outcome in regulation of different actions such as inflammation, polarization, and secretion of macrophages, induction and secretion of T helper cells, and angiogenesis. It is also known that cytokine secretion is highly variable between individuals. These facts red flag the practice of only comparing absolute values of 1 or 2 cytokines in various studies.

Obstructive Thrombosis of Left-Sided Mechanical Heart Valves: Clinical Profile and Thrombolytic Therapy.

Background And Aim Of The Study: Thrombosis of a mechanical prosthetic heart valve is a potentially life-threatening complication associated with a high mortality. Although thrombolytic therapy has been considered highly beneficial in this situation, very few studies have been conducted to monitor the effectiveness of such thrombolytic therapy among Asian populations. Hence, the study aim was to evaluate the clinical profile, efficacy and safety of the thrombolytic agent streptokinase (SK) in patients with obstructive thrombosis of a left-sided mechanical heart valve.