Starting From Scratch: Husbandry Techniques to Establish the First Population of 'Akikiki (Oreomystis bairdi) in Human Care Using Wild-Collected Eggs.

Conservation breeding programs can save species from extinction by establishing assurance populations that provide individuals for achieving species recovery goals in the wild. However, keeping animals in human care can result in the selection of phenotypes that may be suboptimal for post-release survival and reproduction. It is therefore essential that conservation breeding programs provide animals with naturalistic conditions that facilitate the performance of species-typical behaviors, an endeavor that is also a vital aspect of animal welfare.

Best Practices for Education and Training of Resuscitation Teams for In-Hospital Cardiac Arrest.

Background: Survival outcomes following in-hospital cardiac arrest vary significantly across hospitals. Research suggests clinician education and training may play a role. We sought to identify best practices related to the education and training of resuscitation teams.

Hospital length of stay, do not resuscitate orders, and survival for post-cardiac arrest patients in Michigan: A study for the CARES Surveillance Group.

Objective: Current guidelines recommend deferring prognostic decisions for at least 72 h following admission after Out of Hospital cardiac arrest (OHCA). Most non-survivors experience withdrawal of life sustaining therapy (WLST), and early WLST may adversely impact survival. We sought to characterize the hospital length of stay (LOS) and timing of Do Not Resuscitate (DNR) orders (as surrogates for WLST), to assess their relationship to survival following cardiac arrest.

Percutaneous mechanical circulatory support and survival in patients resuscitated from Out of Hospital cardiac arrest: A study from the CARES surveillance group.

Introduction: Maintenance of cardiac function is required for successful outcome after out-of-hospital cardiac arrest (OHCA). Cardiac function can be augmented using a mechanical circulatory support (MCS) device, most commonly an intra-aortic balloon pump (IABP) or Impella®.

Objective: Our objective is to assess whether the use of a MCS is associated with improved survival in patients resuscitated from OHCA in Michigan.

Substantial variation exists in post-cardiac arrest outcomes across Michigan hospitals.

Aim: Resuscitation from out of hospital cardiac arrest (OHCA) requires success across the entire chain of survival. Using a large state-wide registry, we characterized variation in clinical outcomes at hospital discharge in Michigan hospitals.

Methods: We utilized the Michigan Cardiac Arrest Registry to Enhance Survival (CARES) and included adult OHCA subjects with return of spontaneous circulation (ROSC) from 2014 - 2017 that survived to hospital admission.

Baseline Performance of Real-World Clinical Practice Within a Statewide Emergency Medicine Quality Network: The Michigan Emergency Department Improvement Collaborative (MEDIC).

Study Objective: Large-scale quality and performance measurement across unaffiliated hospitals is an important strategy to drive practice change. The Michigan Emergency Department Improvement Collaborative (MEDIC), established in 2015, has baseline performance data to identify practice variation across 15 diverse emergency departments (EDs) on key emergency care quality indicators.

Methods: MEDIC is a unique physician-led partnership supported by a major third-party payer.

A single-institution experience with a brucellosis outbreak in the United States.

Human cases of brucellosis in the United States are primarily limited to imported infections or reservoirs. We describe a brucellosis outbreak involving 8 patients treated at a single hospital in the United States. Standardized precautionary microbiology processes and coordinated collaboration among hospital departments and local health departments assisted in optimally managing this disease at our institution.

Randomized trial of a dry-powder, fibrin sealant in vascular procedures.

Objective: Topical hemostats are important adjuncts for stopping surgical bleeding. The safety and efficacy of Fibrocaps, a dry-powder, fibrin sealant containing human plasma-derived thrombin and fibrinogen, was evaluated in patients undergoing vascular surgical procedures.

Methods: In this single-blind trial (clinicaltrials.

Results from a First-in-Human Trial of a Novel Vascular Sealant.

Background: Suture hole bleeding from synthetic grafts presents a hemostatic challenge. The designs of many vascular sealants are not optimal (non-adherence to wet surfaces, excessive swelling, inflexible). PreveLeak™ (formerly ArterX ((®)) ) is a polyaldehyde-bovine serum albumin-based sealant whose efficacy, safety, and performance were evaluated in this first-in-human study.

Application of watershed deposition tool to estimate from CMAQ simulations the atmospheric deposition of nitrogen to Tampa Bay and its watershed.

Unlabelled: The US. Environmental Protection Agency (EPA) has developed the Watershed Deposition Tool (WDT) to calculate from the Community Multiscale Air Quality (CMAQ) model output the nitrogen, sulfur and mercury deposition rates to watersheds and their sub-basins. The CMAQ model simulates from first principles the transport, transformation, and removal of atmospheric pollutants.

Safety and immunogenicity of recombinant human thrombin: a pooled analysis of results from 10 clinical trials.

Study Objective: To evaluate the safety and immunogenicity of recombinant human thrombin (rThrombin), an active topical stand-alone hemostatic agent.

Design: Analysis of pooled data from 10 rThrombin clinical trials.

Patients: A total of 644 adult and pediatric patients treated with rThrombin; 609 patients were included in the immunogenicity analysis.

Immunogenicity and safety of re-exposure to recombinant human thrombin in surgical hemostasis.

Background: This Phase 4, open-label study evaluated the immunogenicity and safety of a second exposure to recombinant human thrombin (rThrombin) in adult patients with previous exposure to rThrombin.

Study Design: Topical rThrombin was applied as a hemostatic aid during a surgical procedure (day 1). Adverse events and clinical laboratory abnormalities were monitored to day 29 (study end).

Communicating emerging infectious disease outbreaks to the public through local television news: public health officials as potential spokespeople.

Objective: To assess how West Nile virus (WNV) was reported to the American public on local television news and identify the main factors that influenced coverage.

Methods: A representative sample of WNV stories that were reported on 122 local television news stations across the United States during October 2002, covering 67% of the nation's population, were coded for self-efficacy, comparative risk scenarios, symptoms and recommendations, high-risk individuals, and frame. In addition, public service professionals (PSPs) interviewed in the segments were identified.

Persistence of antibodies to the topical hemostat bovine thrombin.

Background: Immunoassays that detect antibovine thrombin product antibodies are not widely available. However, knowing whether these antibodies are present preoperatively would be useful because re-exposure to bovine thrombin-containing products is contraindicated in patients with pre-existing antiproduct antibodies due to the risk of developing immune-mediated coagulopathies. In these exploratory analyses, we characterized one aspect of immune sensitization, the persistence of circulating antibodies after exposure to bovine thrombin product.

Does Local Television News Coverage Cultivate Fatalistic Beliefs about Cancer Prevention?

A substantial proportion of American adults hold fatalistic beliefs about cancer prevention despite evidence that a large proportion of cancer deaths are preventable. Several scholars suggest that news media coverage is one source of these beliefs, but scant evidence has been brought to bear on this assertion. We report findings from two studies that assess the plausibility of the claim that local television (TV) news cultivates fatalistic beliefs about cancer prevention.

Evaluation of recombinant platelet-activating factor acetylhydrolase for reducing the incidence and severity of post-ERCP acute pancreatitis.

Background: Pancreatitis is the most common major complication of diagnostic and therapeutic ERCP. Platelet-activating factor (PAF) has been implicated in the pathophysiologic events associated with acute pancreatitis. Animal and human studies suggested that recombinant PAF acetylhydrolase (rPAF-AH) might ameliorate the severity of acute pancreatitis.

Injury reporting on local TV news: a prime-time opportunity for prevention.

Background: Local television news is America's primary source of information and may be an opportunity to shape public opinion surrounding issues such as injury prevention.

Objective: This study sought to systematically evaluate unintentional-injury coverage on local television news and to identify frequently interviewed public-service professionals and factors associated with discussion of risk factors and prevention.

Methods: Late news broadcasts from 122 local television stations within the U.

Longitudinal studies of inter-alpha inhibitor proteins in severely septic patients: a potential clinical marker and mediator of severe sepsis.

Objective: To determine the clinical relevance and prognostic significance of serial measurement of inter-alpha inhibitor proteins (IalphaIp) in severely septic patients.

Design: A laboratory-based study of serial plasma samples over the first 5 days of severe sepsis from a prospective clinical trial.

Setting: Small business and academic medical center research laboratories.

Local television news reporting of kidney disease.

Background: Local television is the primary news source for the majority of Americans. This study aims to describe how local news reports on kidney disease.

Methods: Using our searchable database of health-related late local news segments from 2002, we identified stories with the key words kidney, hypertension, blood pressure, or diabetes.

Stroke information reported on local television news: a national perspective.

Background And Purpose: Local television news commonly reports on health. This study aimed to characterize local TV news stroke reporting in America.

Methods: Content analysis of stroke stories reported on 122 US local television stations.

Medical news for the public to use? What's on local TV news.

Background: Local television news is the number 1 source of information for most Americans, and media health reporting has increased significantly during the past 10 years.

Objective: To evaluate the health topics and reporting characteristics of health stories on local television news across the United States.

Study Design: Content analysis of full-length broadcasts of local television news from a representative sample of the top 50 US media markets (122 stations).