Outcomes of the overweight and obese major trauma patient in the rural setting.

Purpose: Overweight and obese patients are more prevalent in rural and remote areas and are of major public health concern in Australia. We aimed to evaluate the mortality and morbidity of overweight and obese trauma patients in the rural Australian context.

Method: This was a retrospective cohort study on 207 major trauma patients (injury severity score [ISS] > 12) treated at the Mackay Base Hospital between 2018 and 2021.

Hepatobiliary Actinomycosis, a Rare Presentation of a Rare Disease!

Actinomycosis is a chronic granulomatous infection caused by opportunistic bacteria, Actinomyces. These bacteria lack virulence and cause disease when there is a breach in the integrity of the mucosa. Diagnosis of Actinomycosis is challenging and less than 10% of abdominopelvic cases are diagnosed preoperatively.

Superradiant Instability and Backreaction of Massive Vector Fields around Kerr Black Holes.

We study the growth and saturation of the superradiant instability of a complex, massive vector (Proca) field as it extracts energy and angular momentum from a spinning black hole, using numerical solutions of the full Einstein-Proca equations. We concentrate on a rapidly spinning black hole (a=0.99) and the dominant m=1 azimuthal mode of the Proca field, with real and imaginary components of the field chosen to yield an axisymmetric stress-energy tensor and, hence, spacetime.

Black Hole Spectroscopy with Coherent Mode Stacking.

The measurement of multiple ringdown modes in gravitational waves from binary black hole mergers will allow for testing the fundamental properties of black holes in general relativity and to constrain modified theories of gravity. To enhance the ability of Advanced LIGO/Virgo to perform such tasks, we propose a coherent mode stacking method to search for a chosen target mode within a collection of multiple merger events. We first rescale each signal so that the target mode in each of them has the same frequency and then sum the waveforms constructively.

Clinical utility of abdominal and pelvic ultrasound in the evaluation of right iliac fossa pain in females.

Background: Ultrasound (US) is often the imaging modality of choice in women with acute right iliac fossa (RIF) pain, identifying the appendix in up to 99% of patients. The literature, however, lacks clear guidelines on how ultrasonography should be performed to maximise sensitivity and specificity in such patients. Many centres perform untargeted abdomino-pelvic scans, including organs such as the liver and spleen, which unlikely contribute to the presenting complaint.

The RIPASA score is sensitive and specific for the diagnosis of acute appendicitis in a western population.

Aim: The definitive diagnosis of acute appendicitis (AA) requires histopathological examination. Various clinical diagnostic scoring systems attempt to reduce negative appendectomy rates. The most commonly used in Western Europe and the USA is the Alvarado score.

Laparoscopic total extraperitoneal repair of preoperatively diagnosed bilateral obturator and incidental bilateral femoral herniae.

Obturator hernia (OH), a rare type of hernia, is associated with high morbidity and mortality. Diagnosis is often delayed as clinical symptoms are typically non-specific. OH is frequently associated with other occult inguinopelvic herniae.

Study on colorectal cancer presentation, treatment and follow-up.

Background: Colorectal carcinoma (CRC) is the second most common cancer in women and men affecting 9.7 % population worldwide. Although CRC mortality has been progressively declining since 1990 at a rate of about 3 % per year, it still remains the third most common cause of cancer deaths.

Universality, maximum radiation, and absorption in high-energy collisions of black holes with spin.

We explore the impact of black hole spins on the dynamics of high-energy black hole collisions. We report results from numerical simulations with γ factors up to 2.49 and dimensionless spin parameter χ=+0.

Ultrarelativistic black hole formation.

We study the head-on collision of fluid particles well within the kinetic energy dominated regime (γ = 8 to 12) by numerically solving the Einstein-hydrodynamic equations. We find that the threshold for black hole formation is lower (by a factor of a few) than simple hoop conjecture estimates, and, moreover, near this threshold two distinct apparent horizons first form postcollision and then merge. We argue that this can be understood in terms of a gravitational focusing effect.

Surprises in the evaporation of 2D black holes.

Quantum evaporation of Callan-Giddings-Harvey-Strominger black holes is analyzed in the mean-field approximation, incorporating backreaction. Detailed analytical and numerical calculations show that, while some of the assumptions underlying the standard evaporation paradigm are borne out, several are not. Furthermore, if the black hole is initially macroscopic, the evaporation process exhibits remarkable universal properties (which are distinct from the features observed in the simplified, exactly soluble models).

Black strings, low viscosity fluids, and violation of cosmic censorship.

We describe the behavior of 5-dimensional black strings, subject to the Gregory-Laflamme instability. Beyond the linear level, the evolving strings exhibit a rich dynamics, where at intermediate stages the horizon can be described as a sequence of 3-dimensional spherical black holes joined by black string segments. These segments are themselves subject to a Gregory-Laflamme instability, resulting in a self-similar cascade, where ever-smaller satellite black holes form connected by ever-thinner string segments.

Ultrarelativistic particle collisions.

We present results from numerical solution of the Einstein field equations describing the head-on collision of two solitons boosted to ultrarelativistic energies. We show, for the first time, that at sufficiently high energies the collision leads to black hole formation, consistent with hoop-conjecture arguments. This implies that the nonlinear gravitational interaction between the kinetic energy of the solitons causes gravitational collapse, and that arguments for black hole formation in super-Planck scale particle collisions are robust.

Phase II trial of pegylated liposomal doxorubicin plus docetaxel with and without trastuzumab in metastatic breast cancer: Eastern Cooperative Oncology Group trial E3198.

The purpose of this trial was to determine cardiac toxicity and overall efficacy of the pegylated liposome doxorubicin (PLD)-docetaxel couplet alone if HER2-negative metastatic breast cancer (internal control) or with trastuzumab if HER2-positive disease. Upon central HER2 confirmation, 84 eligible patients received induction with PLD (30 mg/m(2)) and docetaxel (60 mg/m(2)) every 3 weeks (maximum eight cycles), alone if HER2-negative (arm A; N = 38) or plus trastuzumab (4 mg/kg once, then 2 mg/kg weekly) if HER2-positive disease (arm B; N = 46) as first-line therapy. Maintenance therapy (without PLD) allowed.

Cross section, final spin, and zoom-whirl behavior in high-energy black-hole collisions.

We study the collision of two highly boosted equal-mass, nonrotating black holes with generic impact parameter. We find such systems to exhibit zoom-whirl behavior when fine-tuning the impact parameter. Near the threshold of immediate merger the remnant black-hole Kerr parameter can be near maximal (a/M greater, similar 0.

High-energy collision of two black holes.

We study the head-on collision of two highly boosted equal mass, nonrotating black holes. We determine the waveforms, radiated energies, and mode excitation in the center of mass frame for a variety of boosts. For the first time we are able to compare analytic calculations, black-hole perturbation theory, and strong field, nonlinear numerical calculations for this problem.

Evolution of binary black-hole spacetimes.

We describe early success in the evolution of binary black-hole spacetimes with a numerical code based on a generalization of harmonic coordinates. Indications are that with sufficient resolution this scheme is capable of evolving binary systems for enough time to extract information about the orbit, merger, and gravitational waves emitted during the event. As an example we show results from the evolution of a binary composed of two equal mass, nonspinning black holes, through a single plunge orbit, merger, and ringdown.

Critical collapse of a complex scalar field with angular momentum.

We report a new critical solution found at the threshold of axisymmetric gravitational collapse of a complex scalar field with angular momentum. To carry angular momentum the scalar field cannot be axisymmetric; however, its azimuthal dependence is defined so that the resulting stress-energy tensor and spacetime metric are axisymmetric. The critical solution found is nonspherical, discretely self-similar with an echoing exponent Delta=0.

Radiation of benign disease--a South African perspective.

Radiation of benign disease is controversial. The approach of 55 South African radiation oncologists to 14 benign conditions was obtained and compared to available American data. In general, the approach was conservative except in cases of keloids.

Multiple myeloma and amyloidosis of the tongue.

Tongue biopsies of 30 diagnosed cases of multiple myeloma were examined light and electron microscopically and amyloid deposits were identified in 8 patients. Immunochemical typing of amyloid in kappa and lambda subtypes was performed successfully although positive staining of tissue-associated immunoglobulin light chains made reliable identification of amyloid with this technique difficult. Cells of macrophage lineage appear to play a central role in light chain-associated amyloidogenesis.

Age as a prognostic factor in recurrent breast cancer.

The effect of age as a prognostic factor in recurrent breast cancer was studied in 1,168 patients treated on Eastern Cooperative Oncology Group (ECOG) protocols. Survival was significantly shorter in patients less than 35 years of age (P = .03).

A phase I/II investigation of trioxifene mesylate in advanced breast cancer. Clinical and endocrinologic effects.

Tamoxifen and trioxifene are antiestrogens that appear to have different endocrine effects when tested in rats. Whereas tamoxifen has considerable clinical activity, trioxifene is a new antiestrogen with undefined clinical activity. Thirty-six patients were treated with graded doses of trioxifene.

Platelet-bound IgM in autoimmune thrombocytopenia.

Elevated levels of platelet-bound IgG (PA-IgG) are a feature of autoimmune thrombocytopenia (ATP), but it is well documented that this does not occur in all cases. This has led us to investigate the role of platelet-bound IgM (PA-IgM) in these patients using a quantitative enzyme-linked immunosorbent assay (ELISA). Forty-five determinations of PA-IgM and PA-IgG were done on 24 patients with ATP.