Publications by authors named "Prerna Vats"
Article Synopsis
- The study investigates the role of lactate dehydrogenase (LDHA) in lung cancer, showing that its higher expression is linked to poorer survival outcomes for patients.
- Researchers utilized various online databases to analyze gene expression and identified potential regulators of LDHA, such as TMPO-AS1 and hsa-let-7c-5p.
- The findings suggest that targeting LDHA with withanolides might provide a new approach for treating lung cancer, highlighting the importance of regulating metabolic pathways in tumor progression.
Background: Understanding the heterogeneous nature of breast cancer, including the role of LDHA expression regulation via non-coding RNAs in prognosis, is still unknown, highlighting the need for more research into its molecular roles and diagnostic approaches.
Methods: The study utilized various computer tools to analyze the differences between LDHA in tissues and cancer cells. It used data from TIMER 2.