Electrospun Nanofiber Supported Nano/Mesoscale Covalent Organic Frameworks Boost Iodine Sorption.

Covalent Organic Frameworks (COFs) are benchmark materials for iodine sorption, but their use has largely been confined to crystalline bulk forms. In this state, COFs face diffusion limitations leading to slow sorption kinetics. To address this, a series of [2 + 3] imine-linked COFs with varying particle sizes and morphologies (mesospheres, nanoflowers, and bulk) is synthesized.

Engineering the physical properties and photocatalytic activities of a β-ketoenamine COF using continuous flow synthesis.

Covalent Organic Frameworks (COF) having conjugated backbone are an interesting class of metal-free, visible light active, heterogeneous photocatalysts. Interestingly, synthesis of COF using continuous flow process has emerged as an efficient, alternative method when compared to the traditional batch process. Here, we demonstrate the possibility to engineer the physical properties and hence the adsorption and catalytic activities of a β-ketoenamine COF by varying monomer flow rate and microreactor design during the continuous flow synthesis.

Fine-tuning covalent organic frameworks for structure-activity correlation via adsorption and catalytic studies.

In applications utilizing Covalent Organic Frameworks (COFs) for adsorption, the interplay between crystallinity (vis-à-vis surface area) and active sites still remains ambiguous. To address this, the present study introduces three isoreticular COFs-COP-N18 (covalent organic polymer with short-range order), COF-N18 (COF having long-range order), and COF-N27 (semicrystalline COF with pyridyl heteroatoms)-to explore this duality. Through systematic variations in structural order, pore volume, and pore-wall nitrogen content, we aim to establish a structure-activity relationship (SAR) for these COFs via adsorption and catalysis, using CO and I as probes.

Systematic Thiol Decoration in a Redox-Active UiO-66-(SH) Metal-Organic Framework: A Case Study under Oxidative and Reductive Conditions.

The practical applicability of thiolated metal-organic frameworks (MOFs) remains challenging due to their low crystallinity and transient stability. Herein, we present a one-pot solvothermal synthesis process using varying ratios of 2,5-dimercaptoterephthalic acid (DMBD) and 1,4-benzene dicarboxylic acid (100/0, 75/25, 50/50, 25/75, and 0/100) to prepare stable mixed-linker UiO-66-(SH) MOFs (ML-U66SX). For each variant, the effects of different linker ratios on the crystallinity, defectiveness, porosity, and particle size have been discussed in detail.

Correction: Engineering the morphology of palladium nanostructures to tune their electrocatalytic activity in formic acid oxidation reactions.

[This corrects the article DOI: 10.1039/D0NA00798F.].

Synthesis of Metal Nanostructures Using Supercritical Carbon Dioxide: A Green and Upscalable Process.

Metallic nanostructures have numerous applications as industrial catalysts and sensing platforms. Supercritical carbon dioxide (scCO ) is a green medium for the scalable preparation of nanomaterials. Supercritical fluid reactive deposition (SFRD) and other allied techniques can be employed for the mass production of metal nanostructures for various applications.

Engineering the morphology of palladium nanostructures to tune their electrocatalytic activity in formic acid oxidation reactions.

Pd nanomaterials can be cheaper alternative catalysts for the electrocatalytic formic acid oxidation reaction (FAOR) in fuel cells. The size and shape of the nanoparticles and crystal engineering can play a crucial role in enhancing the catalytic activities of Pd nanostructures. A systematic study on the effect of varying the morphology of Pd nanostructures on their catalytic activities for FAOR is reported here.

Preparation, characterization and in vitro cytotoxicity of Fenofibrate and Nabumetone loaded solid lipid nanoparticles.

There is an increasing attention on solid lipid nanoparticles (SLNs) due to their high biocompatibility and ability to enhance bioavailability for poorly water-soluble drugs. Preparation of SLNs that are capable of high drug loading and sustained drug release through hot melt sonication method is reported here. SLNs of palmitic acid and stearic acid loaded with poorly water-soluble drugs, viz.

-Amino-7-azaindole as the ,'-Bidentate Directing Group: Ruthenium-Catalyzed Oxidative Annulation of -(7-Azaindole)benzamides with Alkynes via C-H Bond Activation.

We report a new application of -amino-7-azaindole as a new bidentate-directing group for [Ru(-cymene)Cl]-catalyzed C(sp)-H alkenylation/annulation of -(1-pyrrolo[2,3-]pyridin-1-yl)benzamides with internal alkynes to afford -isoquinolono-7-azaindole via the formation of C-C and C-N bonds. The reaction shows a wide range of substrate scope with different symmetrical and unsymmetrical alkynes, affording the desired product in good to excellent yields. In the case of unsymmetrical alkynes, a highly regioselective product was obtained, which was confirmed by single-crystal X-ray crystallography.

Engineering the Morphology and Particle Size of High Energetic Compounds Using Drop-by-Drop and Drop-to-Drop Solvent-Antisolvent Interaction Methods.

Morphology-controlled precipitation of three powerful organic high energetic compounds (HECs) viz. cyclotrimethylenetrinitramine (RDX), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX), and 2-methyl-1,3,5-trinitrobenzene (TNT) was achieved by two different processes, namely, drop-by-drop (DBD) and drop-to-drop (DTD) solvent-antisolvent interaction methods. Effect of different experimental parameters on the mean size and morphology of the prepared submicron-sized particles of HECs was investigated thoroughly.

A dataset for preparing pristine graphene-palladium nanocomposites using swollen liquid crystal templates.

Pristine graphene (G) has not received much attention as a catalyst support, presumably due to its relative inertness as compared to reduced graphene oxide (RGO). In the present work, we used swollen liquid crystals (SLCs) as nano-reactors for graphene-palladium nanocomposites synthesis. The 'soft' confinement of SLCs directs the growth of palladium (Pd) nanoparticles over the G sheets.

Dendritic Polynitrato Energetic Motifs: Development and Exploration of Physicochemical Behavior through Theoretical and Experimental Approach.

Considering the fundamental and most desirable characteristics of energetic materials, a series of 1,2,3-triazole-based heterocyclic energetic motifs nicely tuned with nitrato (-ONO) functionality were synthesized by a microwave-assisted environmental friendly synthetic approach with good yields. Thermal stability and the nature of evolved gases on decomposition of structurally characterized energetic motifs were analyzed by thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) analysis and Fourier transform infrared coupled with TGA-DSC. The explosiveness of these motifs was explored by calculation of enthalpy of formation and density employing density functional theory, and the detonation performances (detonation pressure and velocity) were explored using EXPLO5_V6.

Solid lipid nanoparticles for the controlled delivery of poorly water soluble non-steroidal anti-inflammatory drugs.

Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (IBP) are among the most prescribed drugs across the globe. However, most NSAIDs are insoluble in water leading them to have poor bioavailability and erratic absorption. Moreover, NSAIDs such as IBP and ketoprofen (KP) have to be administered very frequently due to their short plasma half-life leading to side effects.

Enhancing the Solubility of Fenofibrate by Nanocrystal Formation and Encapsulation.

Development of techniques to enhance bioavailability of drugs having poor water solubility is a big challenge for pharmaceutical industry. Solubility can be enhanced by particle size reduction and encapsulation using hydrophilic polymers. Fenofibrate (FF) is a drug for regulating lipids.

Unusual anti-leukemia activity of nanoformulated naproxen and other non-steroidal anti-inflammatory drugs.

The non-steroidal anti-inflammatory drugs (NSAIDs) are the most widely used pharmaceuticals worldwide. Interestingly, many of them have significant anticancer properties too. However, the poor water solubility of certain NSAIDs limits their application for cancer treatment.

Tuning the surface enhanced Raman scattering and catalytic activities of gold nanorods by controlled coating of platinum.

Galvanic replacement of silver (Ag) by platinum (Pt) on bi-metallic nanorods (NRs) having gold (Au) core and silver shell (Au@Ag) resulted in discontinuous coating of Pt over Au (Au@Pt-DC) NRs. However, a novel method has been developed in this work for the preparation of Au NRs having smooth and continuous coating of Pt (Au@Pt-C NRs) using galvanic replacement reaction of Au@Ag NRs in presence of sulphuric acid. Selective blocking by the bisulfate ions that are adsorbed on Pt surface, preventing Pt on Pt deposition seems to be the mechanism of formation of Au@Pt-C NRs.

Structural studies of high dispersion H3PW12O40/SiO2 solid acid catalysts.

Highly dispersed H(3)PW(12)O(40)/SiO(2) catalysts with loadings between 3.6 and 62.5 wt% have been synthesised and characterised.