Publications by authors named "Prem C Gupta"

Surgical decompression of the thoracic outlet, along with treatment of the involved nerve or vessel, is the accepted treatment modality when indicated. Although neurogenic thoracic outlet syndrome (TOS) is often operated via the axillary approach and venous TOS via the paraclavicular approach, arterial TOS is almost always operated via the supraclavicular approach. The supraclavicular approach provides excellent access to the artery, brachial plexus, phrenic nerve, and the cervical and/or first ribs, along with any bony or fibrous or muscular abnormality that may be causing compression of the neurovascular structures.

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Article Synopsis
  • Thoracic outlet syndrome (TOS) presents a challenge for clinicians due to varied symptom presentations and common overlapping diagnoses, leading to confusion in diagnosis.
  • Even with better imaging techniques and more awareness of TOS, patients often experience misdiagnoses and delays in receiving proper treatment, which can worsen their health outcomes.
  • The authors seek to clarify and summarize current understanding and approaches to diagnosing thoracic outlet syndrome to improve patient management.
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Introduction: Engaging patients living with or at risk of aortic dissection via the Aortic Dissection Collaborative, physician education in vascular genetics was identified as a research priority. We surveyed vascular surgeons to characterize practice patterns, motivations, and barriers regarding aortopathy genetic testing.

Methods: An anonymous 27-question survey was distributed on social media platforms between November and December 2022.

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Case: A 17-year-old male patient presented with Salter-Harris type I hyperextension injury of left distal femur with delayed development of acute limb ischemia secondary to popliteal artery injury.

Conclusion: Popliteal artery injury associated with distal femoral physeal fracture may not be clinically obvious at the time of initial presentation. When initial pulse examination and segmental Doppler measurements are normal, it is important to perform serial examination by experienced examiners because arterial insufficiency may develop over the subsequent 48 hours.

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Article Synopsis
  • Chronic limb-threatening ischemia (CLTI) is a serious condition linked to high risks of mortality, limb amputation, and decreased quality of life, necessitating urgent referral to vascular specialists for management.
  • The term CLTI is preferred as it indicates a spectrum of severity rather than fixed thresholds, defined by the presence of peripheral artery disease alongside critical symptoms like rest pain or non-healing ulcers.
  • A new Global Anatomic Staging System (GLASS) and guidelines for evidence-based revascularization (EBR) are proposed, focusing on key factors like patient risk, limb severity, and anatomical complexity to guide optimal treatment strategies.
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We have investigated intracellular production by T cells and plasma levels of TNF-alpha, IL-2 and IFN-gamma in 12 active and 10 inactive Takayasu's arteritis (TA) patients and 12 healthy controls. The active TA compared to inactive TA and controls had higher TNF-alpha (52.7 +/- 22.

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